|Title||CLOSE: A toolkit for CNA/LOH analysis with Sequencing data|
|Year of Publication||2016|
|Authors||Wang, Xuefeng, Mengjie Chen, Xiaoqing Yu, Natapol Pornputtapong, Hao Chen, Nancy R. Zhang, Scott R Powers, and Michael Krauthammer|
CLOSE is a toolkit for CNA and LOH analysis (as well as CLOnality analysis) with SEquencing data. Current pipeline majorly facilitates the analysis on paired tumor and normal samples. It provides flexible entry points for different users: CLOSE accepts BAM files, VCF files or intial segmention files as input.