Manuscripts and Publications

2016
Martinez CH, Diaz AA, Parulekar AD, Rennard SI, Kanner RE, Hansel NN, Couper D, Holm KE, Hoth KF, Curtis JL et al..  2016.  Age-Related Differences in Health-Related Quality of Life in COPD: An Analysis of the COPDGene and SPIROMICS Cohorts.. Chest. 149(4):927-35.
Woodruff PG, R Barr G, Bleecker E, Christenson SA, Couper D, Curtis JL, Gouskova NA, Hansel NN, Hoffman EA, Kanner RE et al..  2016.  Clinical Significance of Symptoms in Smokers with Preserved Pulmonary Function.. N Engl J Med. 374(19):1811-21.
Sun W, Kechris K, Jacobson S, M Drummond B, Hawkins GA, Yang J, Chen T-H, Quibrera PMiguel, Anderson W, R Barr G et al..  2016.  Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD.. PLoS Genet. 12(8):e1006011.
Guo J, Wang C, Chan K-S, Jin D, Saha PK, Sieren JP, Barr RG, Han MK, Kazerooni E, Cooper CB et al..  2016.  A controlled statistical study to assess measurement variability as a function of test object position and configuration for automated surveillance in a multicenter longitudinal COPD study (SPIROMICS).. Med Phys. 43(5):2598.
Sieren JP, Newell JD, R Barr G, Bleecker ER, Burnette N, Carretta EE, Couper D, Goldin J, Guo J, Han MK et al..  2016.  SPIROMICS Protocol for Multicenter Quantitative Computed Tomography to Phenotype the Lungs.. Am J Respir Crit Care Med. 194(7):794-806.
Putcha N, R Barr G, Han MK, Woodruff PG, Bleecker ER, Kanner RE, Martinez FJ, Smith BM, Tashkin DP, Bowler RP et al..  2016.  Understanding the impact of second-hand smoke exposure on clinical outcomes in participants with COPD in the SPIROMICS cohort.. Thorax. 71:411-420.
2017
Martinez CH, Diaz AA, Meldrum C, Curtis JL, Cooper CB, Pirozzi C, Kanner RE, Paine R, Woodruff PG, Bleecker ER et al..  2017.  Age and Small Airway Imaging Abnormalities in Subjects with and without Airflow Obstruction in SPIROMICS.. Am J Respir Crit Care Med. 195(4):464-472.
Kesimer M, Ford AA, Ceppe A, Radicioni G, Cao R, C Davis W, Doerschuk CM, Alexis NE, Anderson WH, Henderson AG et al..  2017.  Airway Mucin Concentration as a Marker of Chronic Bronchitis.. N Engl J Med. 377(10):911-922.
Hastie AT, Martinez FJ, Curtis JL, Doerschuk CM, Hansel NN, Christenson S, Putcha N, Ortega VE, Li X, R Barr G et al..  2017.  Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort.. Lancet Respir Med. 5(12):956-967.
Keene JD, Jacobson S, Kechris K, Kinney GL, Foreman MG, Doerschuk CM, Make BJ, Curtis JL, Rennard SI, R Barr G et al..  2017.  Biomarkers Predictive of Exacerbations in the SPIROMICS and COPDGene Cohorts.. Am J Respir Crit Care Med. 195(4):473-481.
Nishida K, Brune KA, Putcha N, Mandke P, O'Neal WK, Shade D, Srivastava V, Wang M, Lam H, An SS et al..  2017.  Cigarette smoke disrupts monolayer integrity by altering epithelial cell-cell adhesion and cortical tension.. Am J Physiol Lung Cell Mol Physiol. 313(3):L581-L591.
Hammond E, Sloan C, Newell JD, Sieren JP, Saylor M, Vidal C, Hogue S, De Stefano F, Sieren A, Hoffman EA et al..  2017.  Comparison of low- and ultralow-dose computed tomography protocols for quantitative lung and airway assessment.. Med Phys. 44(9):4747-4757.
Fernández-Baldera A, Hatt CR, Murray S, Hoffman EA, Kazerooni EA, Martinez FJ, Han MK, Galbán CJ.  2017.  Correcting Nonpathological Variation in Longitudinal Parametric Response Maps of CT Scans in COPD Subjects: SPIROMICS.. Tomography. 3(3):138-145.
Bowler RP, Hansel NN, Jacobson S, R Barr G, Make BJ, Han MK, O'Neal WK, Oelsner EC, Casaburi R, Barjaktarevic I et al..  2017.  Electronic Cigarette Use in US Adults at Risk for or with COPD: Analysis from Two Observational Cohorts.. J Gen Intern Med. 32(12):1315-1322.
Han MK, Quibrera PM, Carretta EE, R Barr G, Bleecker ER, Bowler RP, Cooper CB, Comellas A, Couper DJ, Curtis JL et al..  2017.  Frequency of exacerbations in patients with chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.. Lancet Respir Med. 5(8):619-626.
Hobbs BD, de Jong K, Lamontagne M, Bossé Y, Shrine N, Artigas MSoler, Wain LV, Hall IP, Jackson VE, Wyss AB et al..  2017.  Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.. Nat Genet. 49(3):426-432.

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