NumberTitleAuthorsSiteYearJournalPubMed IDPMCID
MS019Parametric response mapping monitors temporal changes on lung CT scans in the subpopulations and intermediate outcome measures in COPD Study (SPIROMICS).Boes, Jennifer L.; Hoff, Benjamin A.; Bule, Maria ; Johnson, Timothy D.; Rehemtulla, Alnawaz ; Chamberlain, Ryan ; Hoffman, Eric A.; Kazerooni, Ella A.; Martinez, Fernando J.; Han, Meilan K.; Ross, Brian D.; Galbán, Craig J.Clinical Center: Michigan (University of Michigan)2015Acad Radiolhttps://pubmed.ncbi.nlm.nih.gov/25442794https://www.ncbi.nlm.nih.gov/pmc/PMC4289437
MS045Cigarette smoke disrupts monolayer integrity by altering epithelial cell-cell adhesion and cortical tension.Nishida, Kristine ; Brune, Kieran A.; Putcha, Nirupama ; Mandke, Pooja ; O'Neal, Wanda K.; Shade, Danny ; Srivastava, Vasudha ; Wang, Menghan ; Lam, Hong ; An, Steven S.; Drummond, Bradley ; Hansel, Nadia N.; Robinson, Douglas N.; Sidhaye, Venkataramana K.Clinical Center: Baltimore (Johns Hopkins University)2017Am J Physiol Lung Cell Mol Physiolhttps://pubmed.ncbi.nlm.nih.gov/28642260https://www.ncbi.nlm.nih.gov/pmc/PMC5625260
MS119A Genetic Risk Score Associated with Chronic Obstructive Pulmonary Disease Susceptibility and Lung Structure on Computed Tomography.Oelsner, Elizabeth C.; Ortega, Victor E.; Smith, Benjamin M.; Nguyen, Jennifer N.; Manichaikul, Ani W.; Hoffman, Eric A.; Guo, Xiuqing ; Taylor, Kent D.; Woodruff, Prescott G.; Couper, David J.; Hansel, Nadia N.; Martinez, Fernando J.; Paine, Robert ; Han, Meilan K.; Cooper, Christopher ; Dransfield, Mark T.; Criner, Gerard ; Krishnan, Jerry A.; Bowler, Russell ; Bleecker, Eugene R.; Peters, Stephen ; Rich, Stephen S.; Meyers, Deborah A.; Rotter, Jerome I.; Barr, Graham Clinical Center: New York (Columbia University)2019Am J Respir Crit Care Medhttps://pubmed.ncbi.nlm.nih.gov/30925230https://www.ncbi.nlm.nih.gov/pmc/PMC6775892
MS026Biomarkers Predictive of Exacerbations in the SPIROMICS and COPDGene Cohorts.Keene, Jason D.; Jacobson, Sean ; Kechris, Katerina ; Kinney, Gregory L.; Foreman, Marilyn G.; Doerschuk, Claire M.; Make, Barry J.; Curtis, Jeffrey L.; Rennard, Stephen I.; Barr, Graham ; Bleecker, Eugene R.; Kanner, Richard E.; Kleerup, Eric C.; Hansel, Nadia N.; Woodruff, Prescott G.; Han, Meilan K.; Paine, Robert ; Martinez, Fernando J.; Bowler, Russell P.; O'Neal, Wanda K.Clinical Center: Denver (National Jewish Health)2017Am J Respir Crit Care Medhttps://pubmed.ncbi.nlm.nih.gov/27579823https://www.ncbi.nlm.nih.gov/pmc/PMC5378424
MS008SPIROMICS Protocol for Multicenter Quantitative Computed Tomography to Phenotype the Lungs.Sieren, Jered P.; Newell, John D.; Barr, Graham ; Bleecker, Eugene R.; Burnette, Nathan ; Carretta, Elizabeth E.; Couper, David ; Goldin, Jonathan ; Guo, Junfeng ; Han, Meilan K.; Hansel, Nadia N.; Kanner, Richard E.; Kazerooni, Ella A.; Martinez, Fernando J.; Rennard, Stephen ; Woodruff, Prescott G.; Hoffman, Eric A.Reading Center: Radiology (University of Iowa)2016Am J Respir Crit Care Medhttps://pubmed.ncbi.nlm.nih.gov/27482984https://www.ncbi.nlm.nih.gov/pmc/PMC5074650
MS163Reversible Airflow Obstruction Predicts Future Chronic Obstructive Pulmonary Disease Development in the SPIROMICS Cohort: An Observational Cohort Study.Buhr, Russell G.; Barjaktarevic, Igor Z.; Quibrera, Miguel ; Bateman, Lori A.; Bleecker, Eugene R.; Couper, David J.; Curtis, Jeffrey L.; Dolezal, Brett A.; Han, Meilan K.; Hansel, Nadia N.; Krishnan, Jerry A.; Martinez, Fernando J.; McKleroy, William ; Paine, Robert ; Rennard, Stephen I.; Tashkin, Donald P.; Woodruff, Prescott G.; Kanner, Richard E.; Cooper, Christopher B.Clinical Center: Los Angeles (University of California at Los Angeles)2022Am J Respir Crit Care Medhttps://pubmed.ncbi.nlm.nih.gov/35549640
MS051Age and Small Airway Imaging Abnormalities in Subjects with and without Airflow Obstruction in SPIROMICS.Martinez, Carlos H.; Diaz, Alejandro A.; Meldrum, Catherine ; Curtis, Jeffrey L.; Cooper, Christopher B.; Pirozzi, Cheryl ; Kanner, Richard E.; Paine, Robert ; Woodruff, Prescott G.; Bleecker, Eugene R.; Hansel, Nadia N.; Barr, Graham ; Marchetti, Nathaniel ; Criner, Gerard J.; Kazerooni, Ella A.; Hoffman, Eric A.; Ross, Brian D.; Galbán, Craig J.; Cigolle, Christine T.; Martinez, Fernando J.; Han, Meilan K.Clinical Center: Michigan (University of Michigan)2017Am J Respir Crit Care Medhttps://pubmed.ncbi.nlm.nih.gov/27564413https://www.ncbi.nlm.nih.gov/pmc/PMC5378423
MS023The Effects of Rare Variants on Lung Function and Emphysema in SPIROMICS.Ortega, Victor E.; Li, Xingnan ; O'Neal, Wanda K.; Lackey, Lela ; Ampleford, Elizabeth ; Hawkins, Gregory A.; Grayeski, Philip J.; Laederach, Alain ; Barjaktarevic, Igor ; Barr, Graham ; Cooper, Christopher ; Couper, David ; Han, Meilan K.; Kanner, Richard E.; Kleerup, Eric C.; Martinez, Fernando J.; Paine, Robert ; Peters, Stephen P.; Pirozzi, Cheryl ; Rennard, Stephen I.; Woodruff, Prescott G.; Hoffman, Eric A.; Meyers, Deborah A.; Bleecker, Eugene R.Clinical Center: Winston-Salem (Wake Forest University Health Sciences)2020Am J Respir Crit Care Medhttps://pubmed.ncbi.nlm.nih.gov/31661293https://www.ncbi.nlm.nih.gov/pmc/PMC7047460
MS082Mucin Concentrations and Peripheral Airway Obstruction in Chronic Obstructive Pulmonary Disease.Kesimer, Mehmet ; Smith, Benjamin M.; Ceppe, Agathe ; Ford, Amina A.; Anderson, Wayne H.; Barr, Graham ; O'Neal, Wanda K.; Boucher, Richard C.Genomics and Informatics Center (University of North Carolina at Chapel Hill)2018Am J Respir Crit Care Medhttps://pubmed.ncbi.nlm.nih.gov/30130124https://www.ncbi.nlm.nih.gov/pmc/PMC6290944
MS013Occupational exposures are associated with worse morbidity in patients with chronic obstructive pulmonary disease.Paulin, Laura M.; Diette, Gregory B.; Blanc, Paul D.; Putcha, Nirupama ; Eisner, Mark D.; Kanner, Richard E.; Belli, Andrew J.; Christenson, Stephanie ; Tashkin, Donald P.; Han, MeiLan ; Barr, Graham ; Hansel, Nadia N.Clinical Center: Baltimore (Johns Hopkins University)2015Am J Respir Crit Care Medhttps://pubmed.ncbi.nlm.nih.gov/25562375https://www.ncbi.nlm.nih.gov/pmc/PMC4384767
MS209Lung Microbiota and Metabolites Collectively Associate with Clinical Outcomes in Milder Stage Chronic Obstructive Pulmonary Disease.Madapoosi, Siddharth S.; Cruickshank-Quinn, Charmion ; Opron, Kristopher ; Erb-Downward, John R.; Begley, Lesa A.; Li, Gen ; Barjaktarevic, Igor ; Barr, Graham ; Comellas, Alejandro P.; Couper, David J.; Cooper, Christopher B.; Freeman, Christine M.; Han, Meilan K.; Kaner, Robert J.; Labaki, Wassim ; Martinez, Fernando J.; Ortega, Victor E.; Peters, Stephen P.; Paine, Robert ; Woodruff, Prescott ; Curtis, Jeffrey L.; Huffnagle, Gary B.; Stringer, Kathleen A.; Bowler, Russell P.; Esther, Charles R.; Reisdorph, Nichole ; Huang, Yvonne J.Clinical Center: Michigan (University of Michigan)2022Am J Respir Crit Care Medhttps://pubmed.ncbi.nlm.nih.gov/35536732
MS178Contribution of Individual and Neighborhood Factors to Racial Disparities in Respiratory Outcomes.Ejike, Chinedu O.; Woo, Han ; Galiatsatos, Panagis ; Paulin, Laura M.; Krishnan, Jerry A.; Cooper, Christopher B.; Couper, David J.; Kanner, Richard E.; Bowler, Russell P.; Hoffman, Eric A.; Comellas, Alejandro P.; Criner, Gerard J.; Barr, Graham ; Martinez, Fernando J.; Han, Meilan K.; Martinez, Carlos H.; Ortega, Victor E.; Parekh, Trisha M.; Christenson, Stephanie A.; Thakur, Neeta ; Baugh, Aaron ; Belz, Daniel C.; Raju, Sarath ; Gassett, Amanda J.; Kaufman, Joel D.; Putcha, Nirupama ; Hansel, Nadia N.Clinical Center: Baltimore (Johns Hopkins University)2021Am J Respir Crit Care Medhttps://pubmed.ncbi.nlm.nih.gov/33007162https://www.ncbi.nlm.nih.gov/pmc/PMC8048743
MS022Association between Emphysema and Chronic Obstructive Pulmonary Disease Outcomes in the COPDGene and SPIROMICS Cohorts: A Post Hoc Analysis of Two Clinical Trials.Han, Meilan K.; Tayob, Nabihah ; Murray, Susan ; Woodruff, Prescott G.; Curtis, Jeffrey L.; Kim, Victor ; Criner, Gerard ; Galbán, Craig J.; Ross, Brian D.; Hoffman, Eric A.; Lynch, David A.; Kazerooni, Ella ; Martinez, Fernando J.Clinical Center: Michigan (University of Michigan)2018Am J Respir Crit Care Medhttps://pubmed.ncbi.nlm.nih.gov/29485901https://www.ncbi.nlm.nih.gov/pmc/PMC6058986
MS087Occupational Exposures and Computed Tomographic Imaging Characteristics in the SPIROMICS Cohort.Paulin, Laura M.; Smith, Benjamin M.; Koch, Abby ; Han, MeiLan ; Hoffman, Eric A.; Martinez, Carlos ; Ejike, Chinedu ; Blanc, Paul D.; Rous, Jennifer ; Barr, Graham ; Peters, Stephen P.; Paine, Robert ; Pirozzi, Cheryl ; Cooper, Christopher B.; Dransfield, Mark T.; Comellas, Alejandro P.; Kanner, Richard E.; Drummond, Brad ; Putcha, Nirupama ; Hansel, Nadia N.Clinical Center: Baltimore (Johns Hopkins University)2018Ann Am Thorac Sochttps://pubmed.ncbi.nlm.nih.gov/30339479https://www.ncbi.nlm.nih.gov/pmc/PMC6322018
MS078Respiratory Symptoms Items from the COPD Assessment Test Identify Ever-Smokers with Preserved Lung Function at Higher Risk for Poor Respiratory Outcomes. An Analysis of the Subpopulations and Intermediate Outcome Measures in COPD Study Cohort.Martinez, Carlos H.; Murray, Susan ; Barr, Graham ; Bleecker, Eugene ; Bowler, Russell P.; Christenson, Stephanie A.; Comellas, Alejandro P.; Cooper, Christopher B.; Couper, David ; Criner, Gerard J.; Curtis, Jeffrey L.; Dransfield, Mark T.; Hansel, Nadia N.; Hoffman, Eric A.; Kanner, Richard E.; Kleerup, Eric ; Krishnan, Jerry A.; Lazarus, Stephen C.; Leidy, Nancy K.; O'Neal, Wanda ; Martinez, Fernando J.; Paine, Robert ; Rennard, Stephen I.; Tashkin, Donald P.; Woodruff, Prescott G.; Han, Meilan K.Clinical Center: Michigan (University of Michigan)2017Ann Am Thorac Sochttps://pubmed.ncbi.nlm.nih.gov/28459622https://www.ncbi.nlm.nih.gov/pmc/PMC5427740
MS122Safety and Tolerability of Comprehensive Research Bronchoscopy in Chronic Obstructive Pulmonary Disease. Results from the SPIROMICS Bronchoscopy Substudy.Wells, Michael ; Arenberg, Douglas A.; Barjaktarevic, Igor ; Bhatt, Surya P.; Bowler, Russell P.; Christenson, Stephanie A.; Couper, David J.; Dransfield, Mark T.; Han, Meilan K.; Hoffman, Eric A.; Kaner, Robert J.; Kim, Victor ; Kleerup, Eric ; Martinez, Fernando J.; Moore, Wendy C.; O'Beirne, Sarah L.; Paine, Robert ; Putcha, Nirupama ; Raman, Sanjeev M.; Barr, Graham ; Rennard, Stephen I.; Woodruff, Prescott G.; Curtis, Jeffrey L.Clinical Center: Birmingham (University of Alabama at Birmingham)2019Ann Am Thorac Sochttps://pubmed.ncbi.nlm.nih.gov/30653926https://www.ncbi.nlm.nih.gov/pmc/PMC6441692
MS174Comparative Impact of Depressive Symptoms and FEV% on Chronic Obstructive Pulmonary Disease.O'Toole, Jacqueline ; Woo, Han ; Putcha, Nirupama ; Cooper, Christopher B.; Woodruff, Prescott ; Kanner, Richard E.; Paine, Robert ; Bowler, Russell P.; Comellas, Alejandro ; Hoth, Karin F.; Krishnan, Jerry A.; Han, MeiLan ; Dransfield, Mark ; Iyer, Anand S.; Couper, David ; Peters, Stephen P.; Criner, Gerard ; Kim, Victor ; Barr, Graham ; Martinez, Fernando J.; Hansel, Nadia N.; Eakin, Michelle N.Clinical Center: Baltimore (Johns Hopkins University)2022Ann Am Thorac Sochttps://pubmed.ncbi.nlm.nih.gov/34410883https://www.ncbi.nlm.nih.gov/pmc/PMC8867359
MS092Rural Residence and Chronic Obstructive Pulmonary Disease Exacerbations. Analysis of the SPIROMICS Cohort.Burkes, Robert M.; Gassett, Amanda J.; Ceppe, Agathe S.; Anderson, Wayne ; O'Neal, Wanda K.; Woodruff, Prescott G.; Krishnan, Jerry A.; Barr, Graham ; Han, Meilan K.; Martinez, Fernando J.; Comellas, Alejandro P.; Lambert, Allison A.; Kaufman, Joel D.; Dransfield, Mark T.; Wells, Michael ; Kanner, Richard E.; Paine, Robert ; Bleecker, Eugene R.; Paulin, Laura M.; Hansel, Nadia N.; Drummond, Bradley Genomics and Informatics Center (University of North Carolina at Chapel Hill)2018Ann Am Thorac Sochttps://pubmed.ncbi.nlm.nih.gov/29584453https://www.ncbi.nlm.nih.gov/pmc/PMC6207115
MS074Clinically Significant and Comorbid Anxiety and Depression Symptoms Predict Severe Respiratory Exacerbations in Smokers: A Post Hoc Analysis of the COPDGene and SPIROMICS CohortsIyer, Anand S.; Parekh, Trisha M.; O'Toole, Jacqueline ; Bhatt, Surya P.; Eakin, Michelle N.; Krishnan, Jerry A.; Yohannes, Abebaw M.; Woodruff, Prescott G.; Cooper, Christopher B.; Kanner, Richard E.; Hanania, Nicola A.; Dransfield, Mark T.; Regan, Elizabeth A.; Hoth, Karin F.; Kim, Victor Clinical Center: Pennsylvania (Temple University)2022Ann Am Thorac Sochttps://pubmed.ncbi.nlm.nih.gov/34343034
MS190Defining Resilience to Smoking-related Lung Disease: A Modified Delphi Approach from SPIROMICS.Oh, Anita L.; Mularski, Richard A.; Barjaktarevic, Igor ; Barr, Graham ; Bowler, Russell P.; Comellas, Alejandro P.; Cooper, Christopher B.; Criner, Gerard J.; Han, Meilan K.; Hansel, Nadia N.; Hoffman, Eric A.; Kanner, Richard E.; Krishnan, Jerry A.; Paine, Robert ; Parekh, Trisha M.; Peters, Stephen P.; Christenson, Stephanie A.; Woodruff, Prescott G.Clinical Center: San Francisco (University of California at San Francisco)2021Ann Am Thorac Sochttps://pubmed.ncbi.nlm.nih.gov/33631079https://www.ncbi.nlm.nih.gov/pmc/PMC8641833
MS094Alignment of Inhaled Chronic Obstructive Pulmonary Disease Therapies with Published Strategies. Analysis of the Global Initiative for Chronic Obstructive Lung Disease Recommendations in SPIROMICS.Ghosh, Sohini ; Anderson, Wayne H.; Putcha, Nirupama ; Han, Meilan K.; Curtis, Jeffrey L.; Criner, Gerard J.; Dransfield, Mark T.; Barr, Graham ; Krishnan, Jerry A.; Lazarus, Stephen C.; Cooper, Christopher B.; Paine, Robert ; Peters, Stephen P.; Hansel, Nadia N.; Martinez, Fernando J.; Drummond, Bradley Genomics and Informatics Center (University of North Carolina at Chapel Hill)2019Ann Am Thorac Sochttps://pubmed.ncbi.nlm.nih.gov/30216731https://www.ncbi.nlm.nih.gov/pmc/PMC6376942
MS075Subpopulations and Intermediate Outcomes in COPD (SPIROMICS) Air Pollution Study DesignHansel, Nadia N.; Paulin, Laura M.; Amanda, Gassett ; Roger, Peng ; Alexis, Neil E.; Fan, Vincent ; Bleecker, Eugene ; Bowler, Russell P.; Comellas, Alejandro P.; Dransfield, Mark T.; Han, Meilan K.; Kim, Victor ; Krishnan, Jerry A.; Pirozzi, Cheryl ; Cooper, Christopher B.; Martinez, Fernando J.; Woodruff, Prescott G.; Patrick, Breysse ; Barr, Graham ; Kaufman, Joel Clinical Center: Baltimore (Johns Hopkins University)2017BJM Open Respiratory Research
MS073Genome-wide association study of lung function and clinical implication in heavy smokers.Li, Xingnan ; Ortega, Victor E.; Ampleford, Elizabeth J.; Barr, Graham ; Christenson, Stephanie A.; Cooper, Christopher B.; Couper, David ; Dransfield, Mark T.; Han, Mei Lan K.; Hansel, Nadia N.; Hoffman, Eric A.; Kanner, Richard E.; Kleerup, Eric C.; Martinez, Fernando J.; Paine, Robert ; Woodruff, Prescott G.; Hawkins, Gregory A.; Bleecker, Eugene R.; Meyers, Deborah A.Clinical Center: Tucson (University of Arizona)2018BMC Med Genethttps://pubmed.ncbi.nlm.nih.gov/30068317https://www.ncbi.nlm.nih.gov/pmc/PMC6090900
MS168Significance of FEV/FEV in Recognition of Early Airway Disease in Smokers at Risk of Development of COPD: Analysis of the SPIROMICS Cohort.Yee, Nathan ; Markovic, Daniela ; Buhr, Russell G.; Fortis, Spyridon ; Arjomandi, Mehrdad ; Couper, David ; Anderson, Wayne H.; Paine, Robert ; Woodruff, Prescott G.; Han, Meilan K.; Martinez, Fernando J.; Barr, Graham ; Wells, James M.; Ortega, Victor E.; Hoffman, Eric A.; Kim, Victor ; Drummond, Bradley ; Bowler, Russell P.; Curtis, Jeffrey L.; Cooper, Christopher B.; Tashkin, Donald P.; Barjaktarevic, Igor Z.Clinical Center: Los Angeles (University of California at Los Angeles)2022Chesthttps://pubmed.ncbi.nlm.nih.gov/34767825https://www.ncbi.nlm.nih.gov/pmc/PMC9005864
MS036Age-Related Differences in Health-Related Quality of Life in COPD: An Analysis of the COPDGene and SPIROMICS Cohorts.Martinez, Carlos H.; Diaz, Alejandro A.; Parulekar, Amit D.; Rennard, Stephen I.; Kanner, Richard E.; Hansel, Nadia N.; Couper, David ; Holm, Kristen E.; Hoth, Karin F.; Curtis, Jeffrey L.; Martinez, Fernando J.; Hanania, Nicola A.; Regan, Elizabeth A.; Paine, Robert ; Cigolle, Christine T.; Han, Meilan K.Clinical Center: Michigan (University of Michigan)2016Chesthttps://pubmed.ncbi.nlm.nih.gov/26836895https://www.ncbi.nlm.nih.gov/pmc/PMC4944781
MS112Aspirin Use and Respiratory Morbidity in COPD: A Propensity Score-Matched Analysis in Subpopulations and Intermediate Outcome Measures in COPD Study.Fawzy, Ashraf ; Putcha, Nirupama ; Aaron, Carrie P.; Bowler, Russell P.; Comellas, Alejandro P.; Cooper, Christopher B.; Dransfield, Mark T.; Han, Meilan K.; Hoffman, Eric A.; Kanner, Richard E.; Krishnan, Jerry A.; Labaki, Wassim W.; Paine, Robert ; Paulin, Laura M.; Peters, Stephen P.; Wise, Robert ; Barr, Graham ; Hansel, Nadia N.Clinical Center: Baltimore (Johns Hopkins University)2019Chesthttps://pubmed.ncbi.nlm.nih.gov/30593776https://www.ncbi.nlm.nih.gov/pmc/PMC6414789
MS158Associations Among 25-Hydroxyvitamin D Levels, Lung Function, and Exacerbation Outcomes in COPD: An Analysis of the SPIROMICS Cohort.Burkes, Robert M.; Ceppe, Agathe S.; Doerschuk, Claire M.; Couper, David ; Hoffman, Eric A.; Comellas, Alejandro P.; Barr, Graham ; Krishnan, Jerry A.; Cooper, Christopher ; Labaki, Wassim W.; Ortega, Victor E.; Wells, Michael ; Criner, Gerard J.; Woodruff, Prescott G.; Bowler, Russell P.; Pirozzi, Cheryl S.; Hansel, Nadia N.; Wise, Robert A.; Brown, Todd T.; Drummond, Bradley Genomics and Informatics Center (University of North Carolina at Chapel Hill)2020Chesthttps://pubmed.ncbi.nlm.nih.gov/31958447https://www.ncbi.nlm.nih.gov/pmc/PMC7118244
MS146Systemic Markers of Inflammation in Smokers With Symptoms Despite Preserved Spirometry in SPIROMICS.Garudadri, Suresh ; Woodruff, Prescott G.; Han, Meilan K.; Curtis, Jeffrey L.; Barr, Graham ; Bleecker, Eugene R.; Bowler, Russell P.; Comellas, Alejandro ; Cooper, Christopher B.; Criner, Gerard ; Dransfield, Mark T.; Hansel, Nadia N.; Paine, Robert ; Krishnan, Jerry A.; Peters, Stephen P.; Hastie, Annette T.; Martinez, Fernando J.; O'Neal, Wanda K.; Couper, David J.; Alexis, Neil E.; Christenson, Stephanie A.Clinical Center: San Francisco (University of California at San Francisco)2019Chesthttps://pubmed.ncbi.nlm.nih.gov/30684474https://www.ncbi.nlm.nih.gov/pmc/PMC6533449
MS191Ratio of FEV/Slow Vital Capacity of < 0.7 Is Associated With Clinical, Functional, and Radiologic Features of Obstructive Lung Disease in Smokers With Preserved Lung Function.Fortis, Spyridon ; Comellas, Alejandro P.; Bhatt, Surya P.; Hoffman, Eric A.; Han, Meilan K.; Bhakta, Nirav R.; Paine, Robert ; Ronish, Bonnie ; Kanner, Richard E.; Dransfield, Mark ; Hoesterey, Daniel ; Buhr, Russell G.; Barr, Graham ; Dolezal, Brett ; Ortega, Victor E.; Drummond, Bradley ; Arjomandi, Mehrdad ; Kaner, Robert J.; Kim, Victor ; Curtis, Jeffrey L.; Bowler, Russell P.; Martinez, Fernando ; Labaki, Wassim W.; Cooper, Christopher B.; O'Neal, Wanda K.; Criner, Gerald ; Hansel, Nadia N.; Krishnan, Jerry A.; Woodruff, Prescott ; Couper, David ; Tashkin, Donald ; Barjaktarevic, Igor Clinical Center: Iowa (University of Iowa)2021Chesthttps://pubmed.ncbi.nlm.nih.gov/33539837https://www.ncbi.nlm.nih.gov/pmc/PMC8295909
MS183Forced Expiratory Flow at 25%-75% Links COPD Physiology to Emphysema and Disease Severity in the SPIROMICS Cohort.Ronish, Bonnie E.; Couper, David J.; Barjaktarevic, Igor Z.; Cooper, Christopher B.; Kanner, Richard E.; Pirozzi, Cheryl S.; Kim, Victor ; Wells, James M.; Han, Meilan K.; Woodruff, Prescott G.; Ortega, Victor E.; Peters, Stephen P.; Hoffman, Eric A.; Buhr, Russell G.; Dolezal, Brett A.; Tashkin, Donald P.; Liou, Theodore G.; Bateman, Lori A.; Schroeder, Joyce D.; Martinez, Fernando J.; Barr, Graham ; Hansel, Nadia N.; Comellas, Alejandro P.; Rennard, Stephen I.; Arjomandi, Mehrdad ; Iii, Robert PaineClinical Center: Utah (University of Utah)2022Chronic Obstr Pulm Dishttps://pubmed.ncbi.nlm.nih.gov/35114743https://www.ncbi.nlm.nih.gov/pmc/PMC9166328
MS116Plasma Cathelicidin is Independently Associated with Reduced Lung Function in COPD: Analysis of the Subpopulations and Intermediate Outcome Measures in COPD Study Cohort.Burkes, Robert M.; Ceppe, Agathe S.; Couper, David J.; Comellas, Alejandro P.; Wells, Michael ; Peters, Stephen P.; Criner, Gerard J.; Kanner, Richard E.; Paine, Robert ; Christenson, Stephanie A.; Cooper, Christopher B.; Barjaktarevic, Igor Z.; Krishnan, Jerry A.; Labaki, Wassim W.; Han, Meilan K.; Curtis, Jeffrey L.; Hansel, Nadia N.; Wise, Robert A.; Drummond, Bradley Genomics and Informatics Center (University of North Carolina at Chapel Hill)2020Chronic Obstr Pulm Dishttps://pubmed.ncbi.nlm.nih.gov/33108110https://www.ncbi.nlm.nih.gov/pmc/PMC7883905
MS207A Risk Prediction Model for Mortality Among Smokers in the COPDGene® Study.Strand, Matthew ; Austin, Erin ; Moll, Matthew ; Pratte, Katherine A.; Regan, Elizabeth A.; Hayden, Lystra P.; Bhatt, Surya P.; Boriek, Aladin M.; Casaburi, Richard ; Silverman, Edwin K.; Fortis, Spyridon ; Ruczinski, Ingo ; Koegler, Harald ; Rossiter, Harry B.; Occhipinti, Mariaelena ; Hanania, Nicola A.; Gebrekristos, Hirut T.; Lynch, David A.; Kunisaki, Ken M.; Young, Kendra A.; Sieren, Jessica C.; Ragland, Margaret ; Hokanson, John E.; Lutz, Sharon M.; Make, Barry J.; Kinney, Gregory L.; Cho, Michael H.; Pistolesi, Massimo ; DeMeo, Dawn L.; Sciurba, Frank C.; Comellas, Alejandro P.; Diaz, Alejandro A.; Barjaktarevic, Igor ; Bowler, Russell P.; Kanner, Richard E.; Peters, Stephen P.; Ortega, Victor E.; Dransfield, Mark T.; Crapo, James D.Clinical Center: Denver (National Jewish Health)2020Chronic Obstr Pulm Dishttps://pubmed.ncbi.nlm.nih.gov/32877963https://www.ncbi.nlm.nih.gov/pmc/PMC7883903
MS158Age-Dependent Associations Between 25-Hydroxy Vitamin D Levels and COPD Symptoms: Analysis of SPIROMICS.Burkes, Robert M.; Couper, David J.; Barjaktarevic, Igor Z.; Cooper, Christopher B.; Labaki, Wassim W.; Han, Meilan K.; Woodruff, Prescott G.; Lazarus, Stephen C.; Parekh, Trisha M.; Paine, Robert ; Comellas, Alejandro P.; Bowler, Russell P.; Loehr, Laura R.; Putcha, Nirupama ; Wise, Robert A.; Brown, Todd T.; Drummond, Bradley Genomics and Informatics Center (University of North Carolina at Chapel Hill)2021Chronic Obstr Pulm Dishttps://pubmed.ncbi.nlm.nih.gov/33829714https://www.ncbi.nlm.nih.gov/pmc/PMC8237982
MS067Characterizing COPD Symptom Variability in the Stable State Utilizing the Evaluating Respiratory Symptoms in COPD InstrumentKrishnan, Jamuna K.; Ancy, Kayley M.; Oromendia, Clara ; Hoffman, Katherine L.; Easthausen, Imaani ; Leidy, Nancy K.; Han, Meilan K.; Bowler, Russell P.; Christenson, Stephanie A.; Couper, David J.; Criner, Gerard J.; Curtis, Jeffrey L.; Dransfield, Mark T.; Hansel, Nadia N.; Iyer, Anand S.; Iii, Robert Paine; Peters, Stephen P.; Wedzicha, Jadwiga A.; Woodruff, Prescott G.; Ballman, Karla V.; Martinez, Fernando J.Weill Cornell Medical Center2022Chronic Obstr Pulm Dishttps://pubmed.ncbi.nlm.nih.gov/35403414https://www.ncbi.nlm.nih.gov/pmc/PMC9166327
MS144Radiographic lung volumes predict progression to COPD in smokers with preserved spirometry in SPIROMICS.Arjomandi, Mehrdad ; Zeng, Siyang ; Barjaktarevic, Igor ; Barr, Graham ; Bleecker, Eugene R.; Bowler, Russell P.; Buhr, Russell G.; Criner, Gerard J.; Comellas, Alejandro P.; Cooper, Christopher B.; Couper, David J.; Curtis, Jeffrey L.; Dransfield, Mark T.; Han, Meilan K.; Hansel, Nadia N.; Hoffman, Eric A.; Kaner, Robert J.; Kanner, Richard E.; Krishnan, Jerry A.; Paine, Robert ; Peters, Stephen P.; Rennard, Stephen I.; Woodruff, Prescott G.Clinical Center: San Francisco (University of California at San Francisco)2019Eur Respir Jhttps://pubmed.ncbi.nlm.nih.gov/31439683https://www.ncbi.nlm.nih.gov/pmc/PMC7089627
MS242Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium.Kasela, Silva ; Ortega, Victor E.; Martorella, Molly ; Garudadri, Suresh ; Nguyen, Jenna ; Ampleford, Elizabeth ; Pasanen, Anu ; Nerella, Srilaxmi ; Buschur, Kristina L.; Barjaktarevic, Igor Z.; Barr, Graham ; Bleecker, Eugene R.; Bowler, Russell P.; Comellas, Alejandro P.; Cooper, Christopher B.; Couper, David J.; Criner, Gerard J.; Curtis, Jeffrey L.; Han, Meilan K.; Hansel, Nadia N.; Hoffman, Eric A.; Kaner, Robert J.; Krishnan, Jerry A.; Martinez, Fernando J.; McDonald, Merry-Lynn N.; Meyers, Deborah A.; Paine, Robert ; Peters, Stephen P.; Castro, Mario ; Denlinger, Loren C.; Erzurum, Serpil C.; Fahy, John V.; Israel, Elliot ; Jarjour, Nizar N.; Levy, Bruce D.; Li, Xingnan ; Moore, Wendy C.; Wenzel, Sally E.; Zein, Joe ; Langelier, Charles ; Woodruff, Prescott G.; Lappalainen, Tuuli ; Christenson, Stephanie A.Clinical Center: San Francisco (University of California at San Francisco)2021Genome Medhttps://pubmed.ncbi.nlm.nih.gov/33883027https://www.ncbi.nlm.nih.gov/pmc/PMC8059115
MS156Modeling residential indoor concentrations of PM , NO , NO , and secondhand smoke in the Subpopulations and Intermediate Outcome Measures in COPD (SPIROMICS) Air study.Zusman, Marina ; Gassett, Amanda J.; Kirwa, Kipruto ; Barr, Graham ; Cooper, Christopher B.; Han, Meilan K.; Kanner, Richard E.; Koehler, Kirsten ; Ortega, Victor E.; Rd, Robert Paine; Paulin, Laura ; Pirozzi, Cheryl ; Rule, Ana ; Hansel, Nadia N.; Kaufman, Joel D.2021Indoor Airhttps://pubmed.ncbi.nlm.nih.gov/33037695https://www.ncbi.nlm.nih.gov/pmc/PMC8202242
MS038Novel Respiratory Disability Score Predicts COPD Exacerbations and Mortality in the SPIROMICS Cohort.Cooper, Christopher B.; Paine, Robert ; Curtis, Jeffrey L.; Kanner, Richard E.; Martinez, Carlos H.; Meldrum, Catherine A.; Bowler, Russell ; O'Neal, Wanda ; Hoffman, Eric A.; Couper, David ; Quibrera, Miguel ; Criner, Gerald ; Dransfield, Mark T.; Han, Meilan K.; Hansel, Nadia N.; Krishnan, Jerry A.; Lazarus, Stephen C.; Peters, Stephen P.; Barr, Graham ; Martinez, Fernando J.; Woodruff, Prescott G.Clinical Center: Los Angeles (University of California at Los Angeles)2020Int J Chron Obstruct Pulmon Dishttps://pubmed.ncbi.nlm.nih.gov/32821092https://www.ncbi.nlm.nih.gov/pmc/PMC7417644
MS006Clinical Significance of Bronchodilator Responsiveness Evaluated by Forced Vital Capacity in COPD: SPIROMICS Cohort Analysis.Barjaktarevic, Igor Z.; Buhr, Russell G.; Wang, Xiaoyan ; Hu, Scott ; Couper, David ; Anderson, Wayne ; Kanner, Richard E.; Iii, Robert Paine; Bhatt, Surya P.; Bhakta, Nirav R.; Arjomandi, Mehrdad ; Kaner, Robert J.; Pirozzi, Cheryl S.; Curtis, Jeffrey L.; O'Neal, Wanda K.; Woodruff, Prescott G.; Han, Meilan K.; Martinez, Fernando J.; Hansel, Nadia ; Wells, James Michael; Ortega, Victor E.; Hoffman, Eric A.; Doerschuk, Claire M.; Kim, Victor ; Dransfield, Mark T.; Drummond, Bradley ; Bowler, Russell ; Criner, Gerard ; Christenson, Stephanie A.; Ronish, Bonnie ; Peters, Stephen P.; Krishnan, Jerry A.; Tashkin, Donald P.; Cooper, Christopher B.Clinical Center: Los Angeles (University of California at Los Angeles)2019Int J Chron Obstruct Pulmon Dishttps://pubmed.ncbi.nlm.nih.gov/31908441https://www.ncbi.nlm.nih.gov/pmc/PMC6930016
MS192Defining Chronic Mucus Hypersecretion Using the CAT in the SPIROMICS Cohort.Stott-Miller, Marni ; Müllerová, Hana ; Miller, Bruce ; Tabberer, Maggie ; Baou, Céline El; Keeley, Tom ; Martinez, Fernando J.; Han, MeiLan ; Dransfield, Mark ; Hansel, Nadia N.; Cooper, Christopher B.; Woodruff, Prescott ; Ortega, Victor E.; Comellas, Alejandro P.; Iii, Robert Paine; Kanner, Richard E.; Anderson, Wayne ; Drummond, Bradley ; Kim, Victor ; Tal-Singer, Ruth ; Lazaar, Aili L.2020Int J Chron Obstruct Pulmon Dishttps://pubmed.ncbi.nlm.nih.gov/33116463https://www.ncbi.nlm.nih.gov/pmc/PMC7568676
MS113Chronic lung disease in adult recurrent tuberculosis survivors in Zimbabwe: a cohort study.Chin, A T.; Rylance, J ; Makumbirofa, S ; Meffert, S ; Vu, T ; Clayton, J ; Mason, P ; Woodruff, P ; Metcalfe, J Clinical Center: San Francisco (University of California at San Francisco)2019Int J Tuberc Lung Dishttps://pubmed.ncbi.nlm.nih.gov/30808453https://www.ncbi.nlm.nih.gov/pmc/PMC6860915
MS206Association Among Chronic Obstructive Pulmonary Disease Severity, Exacerbation Risk, and Anxiety and Depression Symptoms in the SPIROMICS Cohort.Weiss, Jacob R.; Serdenes, Ryan ; Madtha, Uchechukwu ; Zhao, Huaqing ; Kim, Victor ; Lopez-Pastrana, Jahaira ; Eakin, Michelle N.; O'Toole, Jacqueline ; Cooper, Christopher B.; Woodruff, Prescott ; Kanner, Richard E.; Krishnan, Jerry A.; Iyer, Anand S.; Couper, David ; Morrison, Mary F.Clinical Center: Pennsylvania (Temple University)2022J Acad Consult Liaison Psychiatryhttps://pubmed.ncbi.nlm.nih.gov/35948252
MS080Alveolar eosinophilia in current smokers with chronic obstructive pulmonary disease in the SPIROMICS cohort.Martinez, Carlos H.; Li, Sara X.; Hirzel, Andrew J.; Stolberg, Valerie R.; Alexis, Neil E.; Barr, Graham ; Bleecker, Eugene R.; Carretta, Elizabeth E.; Christenson, Stephanie A.; Cooper, Christopher B.; Couper, David J.; Doerschuk, Claire M.; Han, Meilan K.; Hansel, Nadia N.; Hastie, Annette T.; Hoffman, Eric A.; Kaner, Robert J.; Martinez, Fernando J.; Meyers, Deborah A.; O'Neal, Wanda K.; Paine, Robert ; Putcha, Nirupama ; Rennard, Stephen I.; Woodruff, Prescott G.; Zeidler, Michelle ; Curtis, Jeffrey L.; Freeman, Christine M.Clinical Center: Michigan (University of Michigan)2018J Allergy Clin Immunolhttps://pubmed.ncbi.nlm.nih.gov/28916185https://www.ncbi.nlm.nih.gov/pmc/PMC5758424
MS181Elastin-Specific Autoimmunity in Smokers With Thoracic Aortic Aneurysm and Dissection is Independent of Chronic Obstructive Pulmonary Disease.Gu, Bon-Hee ; Choi, Justin C.; Shen, Ying H.; Song, Li-Zhen ; Scheurer, Michael E.; Luong, Amber ; Rodriguez, Antony ; Woodruff, Prescott ; Koth, Laura ; Corry, David B.; Kheradmand, Farrah ; LeMaire, Scott A.Clinical Center: San Francisco (University of California at San Francisco)2019J Am Heart Assochttps://pubmed.ncbi.nlm.nih.gov/30957625https://www.ncbi.nlm.nih.gov/pmc/PMC6507218
MS081An airway epithelial IL-17A response signature identifies a steroid-unresponsive COPD patient subgroup.Christenson, Stephanie A.; van den Berge, Maarten ; Faiz, Alen ; Inkamp, Kai ; Bhakta, Nirav ; Bonser, Luke R.; Zlock, Lorna T.; Barjaktarevic, Igor Z.; Barr, Graham ; Bleecker, Eugene R.; Boucher, Richard C.; Bowler, Russell P.; Comellas, Alejandro P.; Curtis, Jeffrey L.; Han, Meilan K.; Hansel, Nadia N.; Hiemstra, Pieter S.; Kaner, Robert J.; Krishnanm, Jerry A.; Martinez, Fernando J.; O'Neal, Wanda K.; Paine, Robert ; Timens, Wim ; Wells, Michael ; Spira, Avrum ; Erle, David J.; Woodruff, Prescott G.Clinical Center: San Francisco (University of California at San Francisco)2019J Clin Investhttps://pubmed.ncbi.nlm.nih.gov/30383540https://www.ncbi.nlm.nih.gov/pmc/PMC6307967
MS083Electronic Cigarette Use in US Adults at Risk for or with COPD: Analysis from Two Observational Cohorts.Bowler, Russell P.; Hansel, Nadia N.; Jacobson, Sean ; Barr, Graham ; Make, Barry J.; Han, Meilan K.; O'Neal, Wanda K.; Oelsner, Elizabeth C.; Casaburi, Richard ; Barjaktarevic, Igor ; Cooper, Chris ; Foreman, Marilyn ; Wise, Robert A.; DeMeo, Dawn L.; Silverman, Edwin K.; Bailey, William ; Harrington, Kathleen F.; Woodruff, Prescott G.; Drummond, Bradley Clinical Center: Denver (National Jewish Health)2017J Gen Intern Medhttps://pubmed.ncbi.nlm.nih.gov/28884423https://www.ncbi.nlm.nih.gov/pmc/PMC5698219
MS005Comparison of serum, EDTA plasma and P100 plasma for luminex-based biomarker multiplex assays in patients with chronic obstructive pulmonary disease in the SPIROMICS study.O'Neal, Wanda K.; Anderson, Wayne ; Basta, Patricia V.; Carretta, Elizabeth E.; Doerschuk, Claire M.; Barr, Graham ; Bleecker, Eugene R.; Christenson, Stephanie A.; Curtis, Jeffrey L.; Han, Meilan K.; Hansel, Nadia N.; Kanner, Richard E.; Kleerup, Eric C.; Martinez, Fernando J.; Miller, Bruce E.; Peters, Stephen P.; Rennard, Stephen I.; Scholand, Mary Beth; Tal-Singer, Ruth ; Woodruff, Prescott G.; Couper, David J.; Davis, Sonia M.Genomics and Informatics Center (University of North Carolina at Chapel Hill)2014J Transl Medhttps://pubmed.ncbi.nlm.nih.gov/24397870https://www.ncbi.nlm.nih.gov/pmc/PMC3928911
MS017Design of a multi-center immunophenotyping analysis of peripheral blood, sputum and bronchoalveolar lavage fluid in the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS).Freeman, Christine M.; Crudgington, Sean ; Stolberg, Valerie R.; Brown, Jeanette P.; Sonstein, Joanne ; Alexis, Neil E.; Doerschuk, Claire M.; Basta, Patricia V.; Carretta, Elizabeth E.; Couper, David J.; Hastie, Annette T.; Kaner, Robert J.; O'Neal, Wanda K.; Paine, Robert ; Rennard, Stephen I.; Shimbo, Daichi ; Woodruff, Prescott G.; Zeidler, Michelle ; Curtis, Jeffrey L.Clinical Center: Michigan (University of Michigan)2015J Transl Medhttps://pubmed.ncbi.nlm.nih.gov/25622723https://www.ncbi.nlm.nih.gov/pmc/PMC4314767
MS159Association of Dysanapsis With Chronic Obstructive Pulmonary Disease Among Older AdultsSmith, Benjamin M.; Kirby, Miranda ; Hoffman, Eric A.; Kronmal, Richard A.; Aaron, Shawn D.; Allen, Norrina B.; Bertoni, Alain ; Coxson, Harvey O.; Cooper, Chris ; Couper, David J.; Criner, Gerard ; Dransfield, Mark T.; Han, Meilan K.; Hansel, Nadia N.; Jacobs, David R.; Kaufman, Joel D.; Lin, Ching-Long ; Manichaikul, Ani ; Martinez, Fernando J.; Michos, Erin D.; Oelsner, Elizabeth C.; Paine, Robert ; Watson, Karol E.; Benedetti, Andrea ; Tan, Wan C.; Bourbeau, Jean ; Woodruff, Prescott G.; Barr, Graham Clinical Center: New York (Columbia University)2020JAMAhttps://pubmed.ncbi.nlm.nih.gov/32515814https://www.ncbi.nlm.nih.gov/pmc/PMC7284296
MS121Association of Long-term Ambient Ozone Exposure With Respiratory Morbidity in Smokers.Paulin, Laura M.; Gassett, Amanda J.; Alexis, Neil E.; Kirwa, Kipruto ; Kanner, Richard E.; Peters, Stephen ; Krishnan, Jerry A.; Paine, Robert ; Dransfield, Mark ; Woodruff, Prescott G.; Cooper, Christopher B.; Barr, Graham ; Comellas, Alejandro P.; Pirozzi, Cheryl S.; Han, MeiLan ; Hoffman, Eric A.; Martinez, Fernando J.; Woo, Han ; Peng, Roger D.; Fawzy, Ashraf ; Putcha, Nirupama ; Breysse, Patrick N.; Kaufman, Joel D.; Hansel, Nadia N.Clinical Center: Baltimore (Johns Hopkins University)2020JAMA Intern Medhttps://pubmed.ncbi.nlm.nih.gov/31816012https://www.ncbi.nlm.nih.gov/pmc/PMC6902160
MS077Elevated circulating MMP-9 is linked to increased COPD exacerbation risk in SPIROMICS and COPDGene.Wells, Michael ; Parker, Margaret M.; Oster, Robert A.; Bowler, Russ P.; Dransfield, Mark T.; Bhatt, Surya P.; Cho, Michael H.; Kim, Victor ; Curtis, Jeffrey L.; Martinez, Fernando J.; Paine, Robert ; O'Neal, Wanda ; Labaki, Wassim W.; Kaner, Robert J.; Barjaktarevic, Igor ; Han, Meilan K.; Silverman, Edwin K.; Crapo, James D.; Barr, Graham ; Woodruff, Prescott ; Castaldi, Peter J.; Gaggar, Amit Clinical Center: Birmingham (University of Alabama at Birmingham)2018JCI Insighthttps://pubmed.ncbi.nlm.nih.gov/30429371https://www.ncbi.nlm.nih.gov/pmc/PMC6302944
MS194Association of urine mitochondrial DNA with clinical measures of COPD in the SPIROMICS cohortZhang, William Z.; Rice, Michelle C.; Hoffman, Katherine L.; Oromendia, Clara ; Barjaktarevic, Igor Z.; Wells, Michael ; Hastie, Annette T.; Labaki, Wassim W.; Cooper, Christopher B.; Comellas, Alejandro P.; Criner, Gerard J.; Krishnan, Jerry A.; Paine, Robert ; Hansel, Nadia N.; Bowler, Russell P.; Barr, Graham ; Peters, Stephen P.; Woodruff, Prescott G.; Curtis, Jeffrey L.; Han, Meilan K.; Ballman, Karla V.; Martinez, Fernando J.; Choi, Augustine Mk; Nakahira, Kiichi ; Cloonan, Suzanne M.; Choi, Mary E.Weill Cornell Medical Center2020JCI Insighthttps://pubmed.ncbi.nlm.nih.gov/31895696https://www.ncbi.nlm.nih.gov/pmc/PMC7098791
MS001The COPD ontology and toward empowering clinical scientists as ontology engineersgreenberg, jane ; O'Neal, Wanda ; Deshmukh, Rahul ; Lina, Huang ; Mostafa, Javed ; LaVange, Lisa M.; Carretta, Elizabeth E.Genomics and Informatics Center (University of North Carolina at Chapel Hill)2010Journal of Library Metadata
MS219Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.Radicioni, Giorgia ; Ceppe, Agathe ; Ford, Amina A.; Alexis, Neil E.; Barr, Graham ; Bleecker, Eugene R.; Christenson, Stephanie A.; Cooper, Christopher B.; Han, Meilan K.; Hansel, Nadia N.; Hastie, Annette T.; Hoffman, Eric A.; Kanner, Richard E.; Martinez, Fernando J.; Ozkan, Esin ; Paine, Robert ; Woodruff, Prescott G.; O'Neal, Wanda K.; Boucher, Richard C.; Kesimer, Mehmet Genomics and Informatics Center (University of North Carolina at Chapel Hill)2021Lancet Respir Medhttps://pubmed.ncbi.nlm.nih.gov/34058148https://www.ncbi.nlm.nih.gov/pmc/PMC8570975
MS029Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort.Hastie, Annette T.; Martinez, Fernando J.; Curtis, Jeffrey L.; Doerschuk, Claire M.; Hansel, Nadia N.; Christenson, Stephanie ; Putcha, Nirupama ; Ortega, Victor E.; Li, Xingnan ; Barr, Graham ; Carretta, Elizabeth E.; Couper, David J.; Cooper, Christopher B.; Hoffman, Eric A.; Kanner, Richard E.; Kleerup, Eric ; O'Neal, Wanda K.; Paine, Richard ; Peters, Stephen P.; Alexis, Neil E.; Woodruff, Prescott G.; Han, Meilan K.; Meyers, Deborah A.; Bleecker, Eugene R.Clinical Center: Winston-Salem (Wake Forest University Health Sciences)2017Lancet Respir Medhttps://pubmed.ncbi.nlm.nih.gov/29146301https://www.ncbi.nlm.nih.gov/pmc/PMC5849066
MS034Frequency of exacerbations in patients with chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.Han, Meilan K.; Quibrera, Pedro M.; Carretta, Elizabeth E.; Barr, Graham ; Bleecker, Eugene R.; Bowler, Russell P.; Cooper, Christopher B.; Comellas, Alejandro ; Couper, David J.; Curtis, Jeffrey L.; Criner, Gerard ; Dransfield, Mark T.; Hansel, Nadia N.; Hoffman, Eric A.; Kanner, Richard E.; Krishnan, Jerry A.; Martinez, Carlos H.; Pirozzi, Cheryl B.; O'Neal, Wanda K.; Rennard, Stephen ; Tashkin, Donald P.; Wedzicha, Jadwiga A.; Woodruff, Prescott ; Paine, Robert ; Martinez, Fernando J.Clinical Center: Michigan (University of Michigan)2017Lancet Respir Medhttps://pubmed.ncbi.nlm.nih.gov/28668356https://www.ncbi.nlm.nih.gov/pmc/PMC5558856
MS261PLOSL: Population learning followed by one shot learning pulmonary image registration using tissue volume preserving and vesselness constraints.Wang, Di ; Pan, Yue ; Durumeric, Oguz C.; Reinhardt, Joseph M.; Hoffman, Eric A.; Schroeder, Joyce D.; Christensen, Gary E.Reading Center: Radiology (University of Iowa)2022Med Image Analhttps://pubmed.ncbi.nlm.nih.gov/35430476
MS068A controlled statistical study to assess measurement variability as a function of test object position and configuration for automated surveillance in a multicenter longitudinal COPD study (SPIROMICS).Guo, Junfeng ; Wang, Chao ; Chan, Kung-Sik ; Jin, Dakai ; Saha, Punam K.; Sieren, Jered P.; Barr, R G.; Han, Meilan K.; Kazerooni, Ella ; Cooper, Christopher B.; Couper, David ; Newell, John D.; Hoffman, Eric A.Clinical Center: Iowa (University of Iowa)2016Med Physhttps://pubmed.ncbi.nlm.nih.gov/27147369https://www.ncbi.nlm.nih.gov/pmc/PMC4851622
MS008Comparison of low- and ultralow-dose computed tomography protocols for quantitative lung and airway assessment.Hammond, Emily ; Sloan, Chelsea ; Newell, John D.; Sieren, Jered P.; Saylor, Melissa ; Vidal, Craig ; Hogue, Shayna ; De Stefano, Frank ; Sieren, Alexa ; Hoffman, Eric A.; Sieren, Jessica C.Reading Center: Radiology (University of Iowa)2017Med Physhttps://pubmed.ncbi.nlm.nih.gov/28657201https://www.ncbi.nlm.nih.gov/pmc/PMC5603212
MS246A Metabolomic Severity Score for Airflow Obstruction and Emphysema.Godbole, Suneeta ; Labaki, Wassim W.; Pratte, Katherine A.; Hill, Andrew ; Moll, Matthew ; Hastie, Annette T.; Peters, Stephen P.; Gregory, Andrew ; Ortega, Victor E.; Demeo, Dawn ; Cho, Michael H.; Bhatt, Surya P.; Wells, Michael ; Barjaktarevic, Igor ; Stringer, Kathleen A.; Comellas, Alejandro ; O'Neal, Wanda ; Kechris, Katerina ; Bowler, Russell P.Clinical Center: Denver (National Jewish Health)2022Metaboliteshttps://pubmed.ncbi.nlm.nih.gov/35629872https://www.ncbi.nlm.nih.gov/pmc/PMC9143560
MS203Bronchoalveolar Lavage Fluid from COPD Patients Reveals More Compounds Associated with Disease than Matched Plasma.Halper-Stromberg, Eitan ; Gillenwater, Lucas ; Cruickshank-Quinn, Charmion ; O'Neal, Wanda Kay; Reisdorph, Nichole ; Petrache, Irina ; Zhuang, Yonghua ; Labaki, Wassim W.; Curtis, Jeffrey L.; Wells, James ; Rennard, Stephen ; Pratte, Katherine A.; Woodruff, Prescott ; Stringer, Kathleen A.; Kechris, Katerina ; Bowler, Russell P.Clinical Center: Denver (National Jewish Health)2019Metaboliteshttps://pubmed.ncbi.nlm.nih.gov/31349744https://www.ncbi.nlm.nih.gov/pmc/PMC6724137
MS082Airway Mucin Concentration as a Marker of Chronic Bronchitis.Kesimer, Mehmet ; Ford, Amina A.; Ceppe, Agathe ; Radicioni, Giorgia ; Cao, Rui ; Davis, William ; Doerschuk, Claire M.; Alexis, Neil E.; Anderson, Wayne H.; Henderson, Ashley G.; Barr, Graham ; Bleecker, Eugene R.; Christenson, Stephanie A.; Cooper, Christopher B.; Han, Meilan K.; Hansel, Nadia N.; Hastie, Annette T.; Hoffman, Eric A.; Kanner, Richard E.; Martinez, Fernando ; Paine, Robert ; Woodruff, Prescott G.; O'Neal, Wanda K.; Boucher, Richard C.Genomics and Informatics Center (University of North Carolina at Chapel Hill)2017N Engl J Medhttps://pubmed.ncbi.nlm.nih.gov/28877023https://www.ncbi.nlm.nih.gov/pmc/PMC5706541
MS032Clinical Significance of Symptoms in Smokers with Preserved Pulmonary Function.Woodruff, Prescott G.; Barr, Graham ; Bleecker, Eugene ; Christenson, Stephanie A.; Couper, David ; Curtis, Jeffrey L.; Gouskova, Natalia A.; Hansel, Nadia N.; Hoffman, Eric A.; Kanner, Richard E.; Kleerup, Eric ; Lazarus, Stephen C.; Martinez, Fernando J.; Paine, Robert ; Rennard, Stephen ; Tashkin, Donald P.; Han, Meilan K.Clinical Center: San Francisco (University of California at San Francisco)2016N Engl J Medhttps://pubmed.ncbi.nlm.nih.gov/27168432https://www.ncbi.nlm.nih.gov/pmc/PMC4968204
MS072Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.Hobbs, Brian D.; de Jong, Kim ; Lamontagne, Maxime ; Bossé, Yohan ; Shrine, Nick ; Artigas, María Soler; Wain, Louise V.; Hall, Ian P.; Jackson, Victoria E.; Wyss, Annah B.; London, Stephanie J.; North, Kari E.; Franceschini, Nora ; Strachan, David P.; Beaty, Terri H.; Hokanson, John E.; Crapo, James D.; Castaldi, Peter J.; Chase, Robert P.; Bartz, Traci M.; Heckbert, Susan R.; Psaty, Bruce M.; Gharib, Sina A.; Zanen, Pieter ; Lammers, Jan W.; Oudkerk, Matthijs ; Groen, H J.; Locantore, Nicholas ; Tal-Singer, Ruth ; Rennard, Stephen I.; Vestbo, Jørgen ; Timens, Wim ; Paré, Peter D.; Latourelle, Jeanne C.; Dupuis, Josée ; O'Connor, George T.; Wilk, Jemma B.; Kim, Woo Jin; Lee, Mi Kyeong; Oh, Yeon-Mok ; Vonk, Judith M.; de Koning, Harry J.; Leng, Shuguang ; Belinsky, Steven A.; Tesfaigzi, Yohannes ; Manichaikul, Ani ; Wang, Xin-Qun ; Rich, Stephen S.; Barr, Graham ; Sparrow, David ; Litonjua, Augusto A.; Bakke, Per ; Gulsvik, Amund ; Lahousse, Lies ; Brusselle, Guy G.; Stricker, Bruno H.; Uitterlinden, André G.; Ampleford, Elizabeth J.; Bleecker, Eugene R.; Woodruff, Prescott G.; Meyers, Deborah A.; Qiao, Dandi ; Lomas, David A.; Yim, Jae-Joon ; Kim, Deog Kyeom; Hawrylkiewicz, Iwona ; Sliwinski, Pawel ; Hardin, Megan ; Fingerlin, Tasha E.; Schwartz, David A.; Postma, Dirkje S.; MacNee, William ; Tobin, Martin D.; Silverman, Edwin K.; Boezen, Marike ; Cho, Michael H.Clinical Center: Winston-Salem (Wake Forest University Health Sciences)2017Nat Genethttps://pubmed.ncbi.nlm.nih.gov/28166215https://www.ncbi.nlm.nih.gov/pmc/PMC5381275
MS205Plasma Metabolomic Signatures of Chronic Obstructive Pulmonary Disease and the Impact of Genetic Variants on Phenotype-Driven Modules.Gillenwater, Lucas A.; Pratte, Katherine A.; Hobbs, Brian D.; Cho, Michael H.; Zhuang, Yonghua ; Halper-Stromberg, Eitan ; Cruickshank-Quinn, Charmion ; Reisdorph, Nichole ; Petrache, Irina ; Labaki, Wassim W.; O'Neal, Wanda K.; Ortega, Victor E.; Jones, Dean P.; Uppal, Karan ; Jacobson, Sean ; Michelotti, Gregory ; Wendt, Christine H.; Kechris, Katerina J.; Bowler, Russell P.Clinical Center: Denver (National Jewish Health)2020Netw Syst Medhttps://pubmed.ncbi.nlm.nih.gov/33987620https://www.ncbi.nlm.nih.gov/pmc/PMC8109053
MS162Lung microbiota associations with clinical features of COPD in the SPIROMICS cohort.Opron, Kristopher ; Begley, Lesa A.; Erb-Downward, John R.; Freeman, Christine ; Madapoosi, Siddharth ; Alexis, Neil E.; Barjaktarevic, Igor ; Barr, Graham ; Bleecker, Eugene R.; Bowler, Russell P.; Christenson, Stephanie A.; Comellas, Alejandro P.; Cooper, Christopher B.; Couper, David J.; Doerschuk, Claire M.; Dransfield, Mark T.; Han, Meilan K.; Hansel, Nadia N.; Hastie, Annette T.; Hoffman, Eric A.; Kaner, Robert J.; Krishnan, Jerry ; O'Neal, Wanda K.; Ortega, Victor E.; Paine, Robert ; Peters, Stephen P.; Wells, Michael ; Woodruff, Prescott G.; Martinez, Fernando J.; Curtis, Jeffrey L.; Huffnagle, Gary B.; Huang, Yvonne J.Clinical Center: Michigan (University of Michigan)2021NPJ Biofilms Microbiomeshttps://pubmed.ncbi.nlm.nih.gov/33547327https://www.ncbi.nlm.nih.gov/pmc/PMC7865064
MS016Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD.Sun, Wei ; Kechris, Katerina ; Jacobson, Sean ; Drummond, Bradley ; Hawkins, Gregory A.; Yang, Jenny ; Chen, Ting-Huei ; Quibrera, Pedro Miguel; Anderson, Wayne ; Barr, Graham ; Basta, Patricia V.; Bleecker, Eugene R.; Beaty, Terri ; Casaburi, Richard ; Castaldi, Peter ; Cho, Michael H.; Comellas, Alejandro ; Crapo, James D.; Criner, Gerard ; Demeo, Dawn ; Christenson, Stephanie A.; Couper, David J.; Curtis, Jeffrey L.; Doerschuk, Claire M.; Freeman, Christine M.; Gouskova, Natalia A.; Han, Meilan K.; Hanania, Nicola A.; Hansel, Nadia N.; Hersh, Craig P.; Hoffman, Eric A.; Kaner, Robert J.; Kanner, Richard E.; Kleerup, Eric C.; Lutz, Sharon ; Martinez, Fernando J.; Meyers, Deborah A.; Peters, Stephen P.; Regan, Elizabeth A.; Rennard, Stephen I.; Scholand, Mary Beth; Silverman, Edwin K.; Woodruff, Prescott G.; O'Neal, Wanda K.; Bowler, Russell P.Genomics and Informatics Center (University of North Carolina at Chapel Hill)2016PLoS Genethttps://pubmed.ncbi.nlm.nih.gov/27532455https://www.ncbi.nlm.nih.gov/pmc/PMC4988780
MS089Lower serum IgA is associated with COPD exacerbation risk in SPIROMICS.Putcha, Nirupama ; Paul, Gabriel G.; Azar, Antoine ; Wise, Robert A.; O'Neal, Wanda K.; Dransfield, Mark T.; Woodruff, Prescott G.; Curtis, Jeffrey L.; Comellas, Alejandro P.; Drummond, Bradley ; Lambert, Allison A.; Paulin, Laura M.; Fawzy, Ashraf ; Kanner, Richard E.; Paine, Robert ; Han, Meilan K.; Martinez, Fernando J.; Bowler, Russell P.; Barr, Graham ; Hansel, Nadia N.Clinical Center: Baltimore (Johns Hopkins University)2018PLoS Onehttps://pubmed.ncbi.nlm.nih.gov/29649230https://www.ncbi.nlm.nih.gov/pmc/PMC5896903
MS010A simplified score to quantify comorbidity in COPD.Putcha, Nirupama ; Puhan, Milo A.; Drummond, Bradley ; Han, Meilan K.; Regan, Elizabeth A.; Hanania, Nicola A.; Martinez, Carlos H.; Foreman, Marilyn ; Bhatt, Surya P.; Make, Barry ; Ramsdell, Joe ; DeMeo, Dawn L.; Barr, Graham ; Rennard, Stephen I.; Martinez, Fernando ; Silverman, Edwin K.; Crapo, James ; Wise, Robert A.; Hansel, Nadia N.Clinical Center: Baltimore (Johns Hopkins University)2014PLoS Onehttps://pubmed.ncbi.nlm.nih.gov/25514500https://www.ncbi.nlm.nih.gov/pmc/PMC4267736
MS125The influence of social support on COPD outcomes mediated by depression.Turnier, Leonard ; Eakin, Michelle ; Woo, Han ; Dransfield, Mark ; Parekh, Trisha ; Krishnan, Jerry A.; Kanner, Richard ; Cooper, Christopher B.; Woodruff, Prescott G.; Wise, Robert ; Han, Meilan K.; Romero, Karina ; Paulin, Laura M.; Peters, Stephen ; Drummond, Brad ; Bleecker, Eugene R.; Bowler, Russell ; Comellas, Alejandro P.; Couper, David ; Paine, Robert ; Martinez, Fernando ; Barr, Graham ; Putcha, Nirupama ; Hansel, Nadia N.Clinical Center: Baltimore (Johns Hopkins University)2021PLoS Onehttps://pubmed.ncbi.nlm.nih.gov/33730034https://www.ncbi.nlm.nih.gov/pmc/PMC7968645
MS056Variability in objective and subjective measures affects baseline values in studies of patients with COPD.Anderson, Wayne H.; Ha, Jae Wook; Couper, David J.; O'Neal, Wanda K.; Barr, Graham ; Bleecker, Eugene R.; Carretta, Elizabeth E.; Cooper, Christopher B.; Doerschuk, Claire M.; Drummond, Bradley ; Han, Meilan K.; Hansel, Nadia N.; Kim, Victor ; Kleerup, Eric C.; Martinez, Fernando J.; Rennard, Stephen I.; Tashkin, Donald ; Woodruff, Prescott G.; Paine, Robert ; Curtis, Jeffrey L.; Kanner, Richard E.Genomics and Informatics Center (University of North Carolina at Chapel Hill)2017PLoS Onehttps://pubmed.ncbi.nlm.nih.gov/28934249https://www.ncbi.nlm.nih.gov/pmc/PMC5608200
MS053Human airway branch variation and chronic obstructive pulmonary disease.Smith, Benjamin M.; Traboulsi, Hussein ; Austin, John H.M.; Manichaikul, Ani ; Hoffman, Eric A.; Bleecker, Eugene R.; Cardoso, Wellington V.; Cooper, Christopher ; Couper, David J.; Dashnaw, Stephen M.; Guo, Jia ; Han, Meilan K.; Hansel, Nadia N.; Hughes, Emlyn W.; Jacobs, David R.; Kanner, Richard E.; Kaufman, Joel D.; Kleerup, Eric ; Lin, Ching-Long ; Liu, Kiang ; Cascio, Christian M.Lo; Martinez, Fernando J.; Nguyen, Jennifer N.; Prince, Martin R.; Rennard, Stephen ; Rich, Stephen S.; Simon, Leora ; Sun, Yanping ; Watson, Karol E.; Woodruff, Prescott G.; Baglole, Carolyn J.; Barr, Graham Clinical Center: New York (Columbia University)2018Proc Natl Acad Sci U S Ahttps://pubmed.ncbi.nlm.nih.gov/29339516https://www.ncbi.nlm.nih.gov/pmc/PMC5798356
MS095NT-proBNP in stable COPD and future exacerbation risk: Analysis of the SPIROMICS cohort.Labaki, Wassim W.; Xia, Meng ; Murray, Susan ; Curtis, Jeffrey L.; Barr, Graham ; Bhatt, Surya P.; Bleecker, Eugene R.; Hansel, Nadia N.; Cooper, Christopher B.; Dransfield, Mark T.; Wells, Michael ; Hoffman, Eric A.; Kanner, Richard E.; Paine, Robert ; Ortega, Victor E.; Peters, Stephen P.; Krishnan, Jerry A.; Bowler, Russell P.; Couper, David J.; Woodruff, Prescott G.; Martinez, Fernando J.; Martinez, Carlos H.; Han, Meilan K.Clinical Center: Michigan (University of Michigan)2018Respir Medhttps://pubmed.ncbi.nlm.nih.gov/29957287https://www.ncbi.nlm.nih.gov/pmc/PMC6084793
MS041Heterogeneous burden of lung disease in smokers with borderline airflow obstruction.Pirozzi, Cheryl S.; Gu, Tian ; Quibrera, Pedro M.; Carretta, Elizabeth E.; Han, Meilan K.; Murray, Susan ; Cooper, Christopher B.; Tashkin, Donald P.; Kleerup, Eric C.; Barjaktarevic, Igor ; Hoffman, Eric A.; Martinez, Carlos H.; Christenson, Stephanie A.; Hansel, Nadia N.; Barr, Graham ; Bleecker, Eugene R.; Ortega, Victor E.; Martinez, Fernando J.; Kanner, Richard E.; Paine, Robert Clinical Center: Utah (University of Utah)2018Respir Reshttps://pubmed.ncbi.nlm.nih.gov/30454050https://www.ncbi.nlm.nih.gov/pmc/PMC6245799
MS198The matrikine acetyl-proline-glycine-proline and clinical features of COPD: findings from SPIROMICS.Wells, Michael ; Xing, Dongqi ; Viera, Liliana ; Burkes, Robert M.; Wu, Yixin ; Bhatt, Surya P.; Dransfield, Mark T.; Couper, David J.; O'Neal, Wanda ; Hoffman, Eric A.; Gaggar, Amit ; Barjaktarevic, Igor ; Curtis, Jeffrey L.; Labaki, Wassim W.; Han, Mei Lan K.; Freeman, Christine M.; Putcha, Nirupama ; Schlange, Thomas ; Blalock, Edwin Clinical Center: Birmingham (University of Alabama at Birmingham)2019Respir Reshttps://pubmed.ncbi.nlm.nih.gov/31718676https://www.ncbi.nlm.nih.gov/pmc/PMC6852714
MS194Association of plasma mitochondrial DNA with COPD severity and progression in the SPIROMICS cohort.Zhang, William Z.; Hoffman, Katherine L.; Schiffer, Kristen T.; Oromendia, Clara ; Rice, Michelle C.; Barjaktarevic, Igor ; Peters, Stephen P.; Putcha, Nirupama ; Bowler, Russell P.; Wells, Michael ; Couper, David J.; Labaki, Wassim W.; Curtis, Jeffrey L.; Han, Meilan K.; Paine, Robert ; Woodruff, Prescott G.; Criner, Gerard J.; Hansel, Nadia N.; Diaz, Ivan ; Ballman, Karla V.; Nakahira, Kiichi ; Choi, Mary E.; Martinez, Fernando J.; Choi, Augustine M.K.; Cloonan, Suzanne M.Weill Cornell Medical Center2021Respir Reshttps://pubmed.ncbi.nlm.nih.gov/33902556https://www.ncbi.nlm.nih.gov/pmc/PMC8074408
MS107The value of blood cytokines and chemokines in assessing COPD.Bradford, Eric ; Jacobson, Sean ; Varasteh, Jason ; Comellas, Alejandro P.; Woodruff, Prescott ; O'Neal, Wanda ; DeMeo, Dawn L.; Li, Xingnan ; Kim, Victor ; Cho, Michael ; Castaldi, Peter J.; Hersh, Craig ; Silverman, Edwin K.; Crapo, James D.; Kechris, Katerina ; Bowler, Russell P.Clinical Center: Denver (National Jewish Health)2017Respir Reshttps://pubmed.ncbi.nlm.nih.gov/29065892https://www.ncbi.nlm.nih.gov/pmc/PMC5655820
MS093Association of thrombocytosis with COPD morbidity: the SPIROMICS and COPDGene cohorts.Fawzy, Ashraf ; Putcha, Nirupama ; Paulin, Laura M.; Aaron, Carrie P.; Labaki, Wassim W.; Han, Meilan K.; Wise, Robert A.; Kanner, Richard E.; Bowler, Russell P.; Barr, Graham ; Hansel, Nadia N.Clinical Center: Baltimore (Johns Hopkins University)2018Respir Reshttps://pubmed.ncbi.nlm.nih.gov/29373977https://www.ncbi.nlm.nih.gov/pmc/PMC5787242
MS063Imaging-based clusters in current smokers of the COPD cohort associate with clinical characteristics: the SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS).Haghighi, Babak ; Choi, Sanghun ; Choi, Jiwoong ; Hoffman, Eric A.; Comellas, Alejandro P.; Newell, John D.; Barr, Graham ; Bleecker, Eugene ; Cooper, Christopher B.; Couper, David ; Han, Mei Lan; Hansel, Nadia N.; Kanner, Richard E.; Kazerooni, Ella A.; Kleerup, Eric A.C.; Martinez, Fernando J.; O'Neal, Wanda ; Rennard, Stephen I.; Woodruff, Prescott G.; Lin, Ching-Long Clinical Center: Iowa (University of Iowa)2018Respir Reshttps://pubmed.ncbi.nlm.nih.gov/30227877https://www.ncbi.nlm.nih.gov/pmc/PMC6145340
MS142Centrilobular emphysema and coronary artery calcification: mediation analysis in the SPIROMICS cohort.Bhatt, Surya P.; Nath, Hrudaya P.; Kim, Young-Il ; Ramachandran, Rekha ; Watts, Jubal R.; Terry, Nina L.J.; Sonavane, Sushil ; Deshmane, Swati P.; Woodruff, Prescott G.; Oelsner, Elizabeth C.; Bodduluri, Sandeep ; Han, Meilan K.; Labaki, Wassim W.; Wells, Michael ; Martinez, Fernando J.; Barr, Graham ; Dransfield, Mark T.Clinical Center: Birmingham (University of Alabama at Birmingham)2018Respir Reshttps://pubmed.ncbi.nlm.nih.gov/30563576https://www.ncbi.nlm.nih.gov/pmc/PMC6299495
MS145Serum amino acid concentrations and clinical outcomes in smokers: SPIROMICS metabolomics study.Labaki, Wassim W.; Gu, Tian ; Murray, Susan ; Curtis, Jeffrey L.; Yeomans, Larisa ; Bowler, Russell P.; Barr, Graham ; Comellas, Alejandro P.; Hansel, Nadia N.; Cooper, Christopher B.; Barjaktarevic, Igor ; Kanner, Richard E.; Paine, Robert ; McDonald, Merry-Lynn N.; Krishnan, Jerry A.; Peters, Stephen P.; Woodruff, Prescott G.; O'Neal, Wanda K.; Diao, Wenqi ; He, Bei ; Martinez, Fernando J.; Standiford, Theodore J.; Stringer, Kathleen A.; Han, Meilan K.Clinical Center: Michigan (University of Michigan)2019Sci Rephttps://pubmed.ncbi.nlm.nih.gov/31388056https://www.ncbi.nlm.nih.gov/pmc/PMC6684630
MS085Current smoking with or without chronic bronchitis is independently associated with goblet cell hyperplasia in healthy smokers and COPD subjects.Kim, Victor ; Jeong, Stephanie ; Zhao, Huaqing ; Kesimer, Mehmet ; Boucher, Richard C.; Wells, Michael ; Christenson, Stephanie A.; Han, Meilan K.; Dransfield, Mark ; Paine, Robert ; Cooper, Christopher B.; Barjaktarevic, Igor ; Bowler, Russell ; Curtis, Jeffrey L.; Kaner, Robert J.; O'Beirne, Sarah L.; O'Neal, Wanda K.; Rennard, Stephen I.; Martinez, Fernando J.; Woodruff, Prescott G.Clinical Center: Pennsylvania (Temple University)2020Sci Rephttps://pubmed.ncbi.nlm.nih.gov/33208859https://www.ncbi.nlm.nih.gov/pmc/PMC7674445
MS170Increased airway iron parameters and risk for exacerbation in COPD: an analysis from SPIROMICS.Zhang, William Z.; Oromendia, Clara ; Kikkers, Sarah Ann; Butler, James J.; O'Beirne, Sarah ; Kim, Kihwan ; O'Neal, Wanda K.; Freeman, Christine M.; Christenson, Stephanie A.; Peters, Stephen P.; Wells, Michael ; Doerschuk, Claire ; Putcha, Nirupama ; Barjaktarevic, Igor ; Woodruff, Prescott G.; Cooper, Christopher B.; Bowler, Russell P.; Comellas, Alejandro P.; Criner, Gerard J.; Paine, Robert ; Hansel, Nadia N.; Han, Meilan K.; Crystal, Ronald G.; Kaner, Robert J.; Ballman, Karla V.; Curtis, Jeffrey L.; Martinez, Fernando J.; Cloonan, Suzanne M.Weill Cornell Medical Center2020Sci Rephttps://pubmed.ncbi.nlm.nih.gov/32601308https://www.ncbi.nlm.nih.gov/pmc/PMC7324559
MS200Latent traits of lung tissue patterns in former smokers derived by dual channel deep learning in computed tomography images.Li, Frank ; Choi, Jiwoong ; Zou, Chunrui ; Newell, John D.; Comellas, Alejandro P.; Lee, Chang Hyun; Ko, Hongseok ; Barr, Graham ; Bleecker, Eugene R.; Cooper, Christopher B.; Abtin, Fereidoun ; Barjaktarevic, Igor ; Couper, David ; Han, MeiLan ; Hansel, Nadia N.; Kanner, Richard E.; Paine, Robert ; Kazerooni, Ella A.; Martinez, Fernando J.; O'Neal, Wanda ; Rennard, Stephen I.; Smith, Benjamin M.; Woodruff, Prescott G.; Hoffman, Eric A.; Lin, Ching-Long Clinical Center: Iowa (University of Iowa)2021Sci Rephttps://pubmed.ncbi.nlm.nih.gov/33649381https://www.ncbi.nlm.nih.gov/pmc/PMC7921389
MS225Ambient ozone effects on respiratory outcomes among smokers modified by neighborhood poverty: An analysis of SPIROMICS AIRBelz, Daniel C.; Woo, Han ; Putcha, Nirupama ; Paulin, Laura M.; Koehler, Kirsten ; Fawzy, Ashraf ; Alexis, Neil E.; Barr, Graham ; Comellas, Alejandro P.; Cooper, Christopher B.; Couper, David ; Dransfield, Mark ; Gassett, Amanda J.; Han, MeiLan ; Hoffman, Eric A.; Kanner, Richard E.; Krishnan, Jerry A.; Martinez, Fernando J.; Paine, Robert ; Peng, Roger D.; Peters, Stephen ; Pirozzi, Cheryl S.; Woodruff, Prescott G.; Kaufman, Joel D.; Hansel, Nadia N.Clinical Center: Baltimore (Johns Hopkins University)2022Sci Total Environhttps://pubmed.ncbi.nlm.nih.gov/35318050https://www.ncbi.nlm.nih.gov/pmc/PMC9117415
MS012Sleep disruption as a predictor of quality of life among patients in the subpopulations and intermediate outcome measures in COPD study (SPIROMICS).Zeidler, Michelle R.; Martin, Jennifer L.; Kleerup, Eric C.; Schneider, Hartmut ; Mitchell, Michael N.; Hansel, Nadia N.; Sundar, Krishna ; Schotland, Helena ; Basner, Robert C.; Wells, Michael ; Krishnan, Jerry A.; Criner, Gerard J.; Cristenson, Stephanie ; Krachman, Samuel ; Badr, Safwan Clinical Center: Los Angeles (University of California at Los Angeles)2018Sleephttps://pubmed.ncbi.nlm.nih.gov/29534240https://www.ncbi.nlm.nih.gov/pmc/PMC5946919
MS217Risk of COPD exacerbation is increased by poor sleep quality and modified by social adversity.Baugh, Aaron ; Buhr, Russell G.; Quibrera, Pedro ; Barjaktarevic, Igor ; Barr, Graham ; Bowler, Russell ; Han, Meilan King; Kaufman, Joel D.; Koch, Abigail L.; Krishnan, Jerry ; Labaki, Wassim ; Martinez, Fernando J.; Mkorombindo, Takudzwa ; Namen, Andrew ; Ortega, Victor ; Paine, Robert ; Peters, Stephen P.; Schotland, Helena ; Sundar, Krishna ; Zeidler, Michelle R.; Hansel, Nadia N.; Woodruff, Prescott G.; Thakur, Neeta Clinical Center: San Francisco (University of California at San Francisco)2022Sleephttps://pubmed.ncbi.nlm.nih.gov/35665826https://www.ncbi.nlm.nih.gov/pmc/PMC9366643
MS018Comparison of spatially matched airways reveals thinner airway walls in COPD. The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study and the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS).Smith, Benjamin M.; Hoffman, Eric A.; Rabinowitz, Dan ; Bleecker, Eugene ; Christenson, Stephanie ; Couper, David ; Donohue, Kathleen M.; Han, Meilan K.; Hansel, Nadia N.; Kanner, Richard E.; Kleerup, Eric ; Rennard, Stephen ; Barr, Graham Clinical Center: New York (Columbia University)2014Thoraxhttps://pubmed.ncbi.nlm.nih.gov/24928812https://www.ncbi.nlm.nih.gov/pmc/PMC4198462
MS037Understanding the impact of second-hand smoke exposure on clinical outcomes in participants with COPD in the SPIROMICS cohort.Putcha, Nirupama ; Barr, Graham ; Han, Meilan K.; Woodruff, Prescott G.; Bleecker, Eugene R.; Kanner, Richard E.; Martinez, Fernando J.; Smith, Benjamin M.; Tashkin, Donald P.; Bowler, Russell P.; Eisner, Mark D.; Rennard, Stephen I.; Wise, Robert A.; Hansel, Nadia N.Clinical Center: Baltimore (Johns Hopkins University)2016Thoraxhttps://pubmed.ncbi.nlm.nih.gov/26962015https://www.ncbi.nlm.nih.gov/pmc/PMC5235992
MS002Design of the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS).Couper, David ; LaVange, Lisa M.; Han, MeiLan ; Barr, Graham ; Bleecker, Eugene ; Hoffman, Eric A.; Kanner, Richard ; Kleerup, Eric ; Martinez, Fernando J.; Woodruff, Prescott G.; Rennard, Stephen Genomics and Informatics Center (University of North Carolina at Chapel Hill)2014Thoraxhttps://pubmed.ncbi.nlm.nih.gov/24029743https://www.ncbi.nlm.nih.gov/pmc/PMC3954445
MS097Correcting Nonpathological Variation in Longitudinal Parametric Response Maps of CT Scans in COPD Subjects: SPIROMICS.Fernández-Baldera, Antonio ; Hatt, Charles R.; Murray, Susan ; Hoffman, Eric A.; Kazerooni, Ella A.; Martinez, Fernando J.; Han, Meilan K.; Galbán, Craig J.Clinical Center: Michigan (University of Michigan)2017Tomographyhttps://pubmed.ncbi.nlm.nih.gov/29457137https://www.ncbi.nlm.nih.gov/pmc/PMC5812694