Manuscripts Published

90 rows
# Number Title Authors Site Yearsort descending Journal Links
1 MS001 The COPD ontology and toward empowering clinical scientists as ontology engineers greenberg, jane ; O'Neal, Wanda ; Deshmukh, Rahul ; Lina, Huang ; Mostafa, Javed ; LaVange, Lisa M.; Carretta, Elizabeth E. Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2010 Journal of Library Metadata
2 MS010 A simplified score to quantify comorbidity in COPD. Putcha, Nirupama ; Puhan, Milo A.; Drummond, Bradley ; Han, Meilan K.; Regan, Elizabeth A.; Hanania, Nicola A.; Martinez, Carlos H.; Foreman, Marilyn ; Bhatt, Surya P.; Make, Barry ; Ramsdell, Joe ; DeMeo, Dawn L.; Barr, Graham ; Rennard, Stephen I.; Martinez, Fernando ; Silverman, Edwin K.; Crapo, James ; Wise, Robert A.; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2014 PLoS One 25514500
PMC4267736
3 MS018 Comparison of spatially matched airways reveals thinner airway walls in COPD. The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study and the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS). Smith, Benjamin M.; Hoffman, Eric A.; Rabinowitz, Dan ; Bleecker, Eugene ; Christenson, Stephanie ; Couper, David ; Donohue, Kathleen M.; Han, Meilan K.; Hansel, Nadia N.; Kanner, Richard E.; Kleerup, Eric ; Rennard, Stephen ; Barr, Graham Clinical Center: New York (Columbia University) 2014 Thorax 24928812
PMC4198462
4 MS005 Comparison of serum, EDTA plasma and P100 plasma for luminex-based biomarker multiplex assays in patients with chronic obstructive pulmonary disease in the SPIROMICS study. O'Neal, Wanda K.; Anderson, Wayne ; Basta, Patricia V.; Carretta, Elizabeth E.; Doerschuk, Claire M.; Barr, Graham ; Bleecker, Eugene R.; Christenson, Stephanie A.; Curtis, Jeffrey L.; Han, Meilan K.; Hansel, Nadia N.; Kanner, Richard E.; Kleerup, Eric C.; Martinez, Fernando J.; Miller, Bruce E.; Peters, Stephen P.; Rennard, Stephen I.; Scholand, Mary Beth; Tal-Singer, Ruth ; Woodruff, Prescott G.; Couper, David J.; Davis, Sonia M. Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2014 J Transl Med 24397870
PMC3928911
5 MS002 Design of the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS). Couper, David ; LaVange, Lisa M.; Han, MeiLan ; Barr, Graham ; Bleecker, Eugene ; Hoffman, Eric A.; Kanner, Richard ; Kleerup, Eric ; Martinez, Fernando J.; Woodruff, Prescott G.; Rennard, Stephen Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2014 Thorax 24029743
PMC3954445
6 MS013 Occupational exposures are associated with worse morbidity in patients with chronic obstructive pulmonary disease. Paulin, Laura M.; Diette, Gregory B.; Blanc, Paul D.; Putcha, Nirupama ; Eisner, Mark D.; Kanner, Richard E.; Belli, Andrew J.; Christenson, Stephanie ; Tashkin, Donald P.; Han, MeiLan ; Barr, Graham ; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2015 Am J Respir Crit Care Med 25562375
PMC4384767
7 MS019 Parametric response mapping monitors temporal changes on lung CT scans in the subpopulations and intermediate outcome measures in COPD Study (SPIROMICS). Boes, Jennifer L.; Hoff, Benjamin A.; Bule, Maria ; Johnson, Timothy D.; Rehemtulla, Alnawaz ; Chamberlain, Ryan ; Hoffman, Eric A.; Kazerooni, Ella A.; Martinez, Fernando J.; Han, Meilan K.; Ross, Brian D.; Galbán, Craig J. Clinical Center: Michigan (University of Michigan) 2015 Acad Radiol 25442794
PMC4289437
8 MS017 Design of a multi-center immunophenotyping analysis of peripheral blood, sputum and bronchoalveolar lavage fluid in the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS). Freeman, Christine M.; Crudgington, Sean ; Stolberg, Valerie R.; Brown, Jeanette P.; Sonstein, Joanne ; Alexis, Neil E.; Doerschuk, Claire M.; Basta, Patricia V.; Carretta, Elizabeth E.; Couper, David J.; Hastie, Annette T.; Kaner, Robert J.; O'Neal, Wanda K.; Paine, Robert ; Rennard, Stephen I.; Shimbo, Daichi ; Woodruff, Prescott G.; Zeidler, Michelle ; Curtis, Jeffrey L. Clinical Center: Michigan (University of Michigan) 2015 J Transl Med 25622723
PMC4314767
9 MS008 SPIROMICS Protocol for Multicenter Quantitative Computed Tomography to Phenotype the Lungs. Sieren, Jered P.; Newell, John D.; Barr, Graham ; Bleecker, Eugene R.; Burnette, Nathan ; Carretta, Elizabeth E.; Couper, David ; Goldin, Jonathan ; Guo, Junfeng ; Han, Meilan K.; Hansel, Nadia N.; Kanner, Richard E.; Kazerooni, Ella A.; Martinez, Fernando J.; Rennard, Stephen ; Woodruff, Prescott G.; Hoffman, Eric A. Reading Center: Radiology (University of Iowa) 2016 Am J Respir Crit Care Med 27482984
PMC5074650
10 MS036 Age-Related Differences in Health-Related Quality of Life in COPD: An Analysis of the COPDGene and SPIROMICS Cohorts. Martinez, Carlos H.; Diaz, Alejandro A.; Parulekar, Amit D.; Rennard, Stephen I.; Kanner, Richard E.; Hansel, Nadia N.; Couper, David ; Holm, Kristen E.; Hoth, Karin F.; Curtis, Jeffrey L.; Martinez, Fernando J.; Hanania, Nicola A.; Regan, Elizabeth A.; Paine, Robert ; Cigolle, Christine T.; Han, Meilan K. Clinical Center: Michigan (University of Michigan) 2016 Chest 26836895
PMC4944781
11 MS032 Clinical Significance of Symptoms in Smokers with Preserved Pulmonary Function. Woodruff, Prescott G.; Barr, Graham ; Bleecker, Eugene ; Christenson, Stephanie A.; Couper, David ; Curtis, Jeffrey L.; Gouskova, Natalia A.; Hansel, Nadia N.; Hoffman, Eric A.; Kanner, Richard E.; Kleerup, Eric ; Lazarus, Stephen C.; Martinez, Fernando J.; Paine, Robert ; Rennard, Stephen ; Tashkin, Donald P.; Han, Meilan K. Clinical Center: San Francisco (University of California at San Francisco) 2016 N Engl J Med 27168432
PMC4968204
12 MS037 Understanding the impact of second-hand smoke exposure on clinical outcomes in participants with COPD in the SPIROMICS cohort. Putcha, Nirupama ; Barr, Graham ; Han, Meilan K.; Woodruff, Prescott G.; Bleecker, Eugene R.; Kanner, Richard E.; Martinez, Fernando J.; Smith, Benjamin M.; Tashkin, Donald P.; Bowler, Russell P.; Eisner, Mark D.; Rennard, Stephen I.; Wise, Robert A.; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2016 Thorax 26962015
PMC5235992
13 MS068 A controlled statistical study to assess measurement variability as a function of test object position and configuration for automated surveillance in a multicenter longitudinal COPD study (SPIROMICS). Guo, Junfeng ; Wang, Chao ; Chan, Kung-Sik ; Jin, Dakai ; Saha, Punam K.; Sieren, Jered P.; Barr, R G.; Han, Meilan K.; Kazerooni, Ella ; Cooper, Christopher B.; Couper, David ; Newell, John D.; Hoffman, Eric A. Clinical Center: Iowa (University of Iowa) 2016 Med Phys 27147369
PMC4851622
14 MS016 Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD. Sun, Wei ; Kechris, Katerina ; Jacobson, Sean ; Drummond, Bradley ; Hawkins, Gregory A.; Yang, Jenny ; Chen, Ting-Huei ; Quibrera, Pedro Miguel; Anderson, Wayne ; Barr, Graham ; Basta, Patricia V.; Bleecker, Eugene R.; Beaty, Terri ; Casaburi, Richard ; Castaldi, Peter ; Cho, Michael H.; Comellas, Alejandro ; Crapo, James D.; Criner, Gerard ; Demeo, Dawn ; Christenson, Stephanie A.; Couper, David J.; Curtis, Jeffrey L.; Doerschuk, Claire M.; Freeman, Christine M.; Gouskova, Natalia A.; Han, Meilan K.; Hanania, Nicola A.; Hansel, Nadia N.; Hersh, Craig P.; Hoffman, Eric A.; Kaner, Robert J.; Kanner, Richard E.; Kleerup, Eric C.; Lutz, Sharon ; Martinez, Fernando J.; Meyers, Deborah A.; Peters, Stephen P.; Regan, Elizabeth A.; Rennard, Stephen I.; Scholand, Mary Beth; Silverman, Edwin K.; Woodruff, Prescott G.; O'Neal, Wanda K.; Bowler, Russell P. Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2016 PLoS Genet 27532455
PMC4988780
15 MS026 Biomarkers Predictive of Exacerbations in the SPIROMICS and COPDGene Cohorts. Keene, Jason D.; Jacobson, Sean ; Kechris, Katerina ; Kinney, Gregory L.; Foreman, Marilyn G.; Doerschuk, Claire M.; Make, Barry J.; Curtis, Jeffrey L.; Rennard, Stephen I.; Barr, Graham ; Bleecker, Eugene R.; Kanner, Richard E.; Kleerup, Eric C.; Hansel, Nadia N.; Woodruff, Prescott G.; Han, Meilan K.; Paine, Robert ; Martinez, Fernando J.; Bowler, Russell P.; O'Neal, Wanda K. Clinical Center: Denver (National Jewish Health) 2017 Am J Respir Crit Care Med 27579823
PMC5378424
16 MS078 Respiratory Symptoms Items from the COPD Assessment Test Identify Ever-Smokers with Preserved Lung Function at Higher Risk for Poor Respiratory Outcomes. An Analysis of the Subpopulations and Intermediate Outcome Measures in COPD Study Cohort. Martinez, Carlos H.; Murray, Susan ; Barr, Graham ; Bleecker, Eugene ; Bowler, Russell P.; Christenson, Stephanie A.; Comellas, Alejandro P.; Cooper, Christopher B.; Couper, David ; Criner, Gerard J.; Curtis, Jeffrey L.; Dransfield, Mark T.; Hansel, Nadia N.; Hoffman, Eric A.; Kanner, Richard E.; Kleerup, Eric ; Krishnan, Jerry A.; Lazarus, Stephen C.; Leidy, Nancy K.; O'Neal, Wanda ; Martinez, Fernando J.; Paine, Robert ; Rennard, Stephen I.; Tashkin, Donald P.; Woodruff, Prescott G.; Han, Meilan K. Clinical Center: Michigan (University of Michigan) 2017 Ann Am Thorac Soc 28459622
PMC5427740
17 MS082 Airway Mucin Concentration as a Marker of Chronic Bronchitis. Kesimer, Mehmet ; Ford, Amina A.; Ceppe, Agathe ; Radicioni, Giorgia ; Cao, Rui ; Davis, William ; Doerschuk, Claire M.; Alexis, Neil E.; Anderson, Wayne H.; Henderson, Ashley G.; Barr, Graham ; Bleecker, Eugene R.; Christenson, Stephanie A.; Cooper, Christopher B.; Han, Meilan K.; Hansel, Nadia N.; Hastie, Annette T.; Hoffman, Eric A.; Kanner, Richard E.; Martinez, Fernando ; Paine, Robert ; Woodruff, Prescott G.; O'Neal, Wanda K.; Boucher, Richard C. Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2017 N Engl J Med 28877023
PMC5706541
18 MS107 The value of blood cytokines and chemokines in assessing COPD. Bradford, Eric ; Jacobson, Sean ; Varasteh, Jason ; Comellas, Alejandro P.; Woodruff, Prescott ; O'Neal, Wanda ; DeMeo, Dawn L.; Li, Xingnan ; Kim, Victor ; Cho, Michael ; Castaldi, Peter J.; Hersh, Craig ; Silverman, Edwin K.; Crapo, James D.; Kechris, Katerina ; Bowler, Russell P. Clinical Center: Denver (National Jewish Health) 2017 Respir Res 29065892
PMC5655820
19 MS051 Age and Small Airway Imaging Abnormalities in Subjects with and without Airflow Obstruction in SPIROMICS. Martinez, Carlos H.; Diaz, Alejandro A.; Meldrum, Catherine ; Curtis, Jeffrey L.; Cooper, Christopher B.; Pirozzi, Cheryl ; Kanner, Richard E.; Paine, Robert ; Woodruff, Prescott G.; Bleecker, Eugene R.; Hansel, Nadia N.; Barr, Graham ; Marchetti, Nathaniel ; Criner, Gerard J.; Kazerooni, Ella A.; Hoffman, Eric A.; Ross, Brian D.; Galbán, Craig J.; Cigolle, Christine T.; Martinez, Fernando J.; Han, Meilan K. Clinical Center: Michigan (University of Michigan) 2017 Am J Respir Crit Care Med 27564413
PMC5378423
20 MS072 Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis. Hobbs, Brian D.; de Jong, Kim ; Lamontagne, Maxime ; Bossé, Yohan ; Shrine, Nick ; Artigas, María Soler; Wain, Louise V.; Hall, Ian P.; Jackson, Victoria E.; Wyss, Annah B.; London, Stephanie J.; North, Kari E.; Franceschini, Nora ; Strachan, David P.; Beaty, Terri H.; Hokanson, John E.; Crapo, James D.; Castaldi, Peter J.; Chase, Robert P.; Bartz, Traci M.; Heckbert, Susan R.; Psaty, Bruce M.; Gharib, Sina A.; Zanen, Pieter ; Lammers, Jan W.; Oudkerk, Matthijs ; Groen, H J.; Locantore, Nicholas ; Tal-Singer, Ruth ; Rennard, Stephen I.; Vestbo, Jørgen ; Timens, Wim ; Paré, Peter D.; Latourelle, Jeanne C.; Dupuis, Josée ; O'Connor, George T.; Wilk, Jemma B.; Kim, Woo Jin; Lee, Mi Kyeong; Oh, Yeon-Mok ; Vonk, Judith M.; de Koning, Harry J.; Leng, Shuguang ; Belinsky, Steven A.; Tesfaigzi, Yohannes ; Manichaikul, Ani ; Wang, Xin-Qun ; Rich, Stephen S.; Barr, Graham ; Sparrow, David ; Litonjua, Augusto A.; Bakke, Per ; Gulsvik, Amund ; Lahousse, Lies ; Brusselle, Guy G.; Stricker, Bruno H.; Uitterlinden, André G.; Ampleford, Elizabeth J.; Bleecker, Eugene R.; Woodruff, Prescott G.; Meyers, Deborah A.; Qiao, Dandi ; Lomas, David A.; Yim, Jae-Joon ; Kim, Deog Kyeom; Hawrylkiewicz, Iwona ; Sliwinski, Pawel ; Hardin, Megan ; Fingerlin, Tasha E.; Schwartz, David A.; Postma, Dirkje S.; MacNee, William ; Tobin, Martin D.; Silverman, Edwin K.; Boezen, Marike ; Cho, Michael H. Clinical Center: Winston-Salem (Wake Forest University Health Sciences) 2017 Nat Genet 28166215
PMC5381275
21 MS045 Cigarette smoke disrupts monolayer integrity by altering epithelial cell-cell adhesion and cortical tension. Nishida, Kristine ; Brune, Kieran A.; Putcha, Nirupama ; Mandke, Pooja ; O'Neal, Wanda K.; Shade, Danny ; Srivastava, Vasudha ; Wang, Menghan ; Lam, Hong ; An, Steven S.; Drummond, Bradley ; Hansel, Nadia N.; Robinson, Douglas N.; Sidhaye, Venkataramana K. Clinical Center: Baltimore (Johns Hopkins University) 2017 Am J Physiol Lung Cell Mol Physiol 28642260
PMC5625260
22 MS056 Variability in objective and subjective measures affects baseline values in studies of patients with COPD. Anderson, Wayne H.; Ha, Jae Wook; Couper, David J.; O'Neal, Wanda K.; Barr, Graham ; Bleecker, Eugene R.; Carretta, Elizabeth E.; Cooper, Christopher B.; Doerschuk, Claire M.; Drummond, Bradley ; Han, Meilan K.; Hansel, Nadia N.; Kim, Victor ; Kleerup, Eric C.; Martinez, Fernando J.; Rennard, Stephen I.; Tashkin, Donald ; Woodruff, Prescott G.; Paine, Robert ; Curtis, Jeffrey L.; Kanner, Richard E. Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2017 PLoS One 28934249
PMC5608200
23 MS083 Electronic Cigarette Use in US Adults at Risk for or with COPD: Analysis from Two Observational Cohorts. Bowler, Russell P.; Hansel, Nadia N.; Jacobson, Sean ; Barr, Graham ; Make, Barry J.; Han, Meilan K.; O'Neal, Wanda K.; Oelsner, Elizabeth C.; Casaburi, Richard ; Barjaktarevic, Igor ; Cooper, Chris ; Foreman, Marilyn ; Wise, Robert A.; DeMeo, Dawn L.; Silverman, Edwin K.; Bailey, William ; Harrington, Kathleen F.; Woodruff, Prescott G.; Drummond, Bradley Clinical Center: Denver (National Jewish Health) 2017 J Gen Intern Med 28884423
PMC5698219
24 MS029 Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort. Hastie, Annette T.; Martinez, Fernando J.; Curtis, Jeffrey L.; Doerschuk, Claire M.; Hansel, Nadia N.; Christenson, Stephanie ; Putcha, Nirupama ; Ortega, Victor E.; Li, Xingnan ; Barr, Graham ; Carretta, Elizabeth E.; Couper, David J.; Cooper, Christopher B.; Hoffman, Eric A.; Kanner, Richard E.; Kleerup, Eric ; O'Neal, Wanda K.; Paine, Richard ; Peters, Stephen P.; Alexis, Neil E.; Woodruff, Prescott G.; Han, Meilan K.; Meyers, Deborah A.; Bleecker, Eugene R. Clinical Center: Winston-Salem (Wake Forest University Health Sciences) 2017 Lancet Respir Med 29146301
PMC5849066
25 MS097 Correcting Nonpathological Variation in Longitudinal Parametric Response Maps of CT Scans in COPD Subjects: SPIROMICS. Fernández-Baldera, Antonio ; Hatt, Charles R.; Murray, Susan ; Hoffman, Eric A.; Kazerooni, Ella A.; Martinez, Fernando J.; Han, Meilan K.; Galbán, Craig J. Clinical Center: Michigan (University of Michigan) 2017 Tomography 29457137
PMC5812694
26 MS075 Subpopulations and Intermediate Outcomes in COPD (SPIROMICS) Air Pollution Study Design Hansel, Nadia N.; Paulin, Laura M.; Amanda, Gassett ; Roger, Peng ; Alexis, Neil E.; Fan, Vincent ; Bleecker, Eugene ; Bowler, Russell P.; Comellas, Alejandro P.; Dransfield, Mark T.; Han, Meilan K.; Kim, Victor ; Krishnan, Jerry A.; Pirozzi, Cheryl ; Cooper, Christopher B.; Martinez, Fernando J.; Woodruff, Prescott G.; Patrick, Breysse ; Barr, Graham ; Kaufman, Joel Clinical Center: Baltimore (Johns Hopkins University) 2017 BJM Open Respiratory Research
27 MS034 Frequency of exacerbations in patients with chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort. Han, Meilan K.; Quibrera, Pedro M.; Carretta, Elizabeth E.; Barr, Graham ; Bleecker, Eugene R.; Bowler, Russell P.; Cooper, Christopher B.; Comellas, Alejandro ; Couper, David J.; Curtis, Jeffrey L.; Criner, Gerard ; Dransfield, Mark T.; Hansel, Nadia N.; Hoffman, Eric A.; Kanner, Richard E.; Krishnan, Jerry A.; Martinez, Carlos H.; Pirozzi, Cheryl B.; O'Neal, Wanda K.; Rennard, Stephen ; Tashkin, Donald P.; Wedzicha, Jadwiga A.; Woodruff, Prescott ; Paine, Robert ; Martinez, Fernando J. Clinical Center: Michigan (University of Michigan) 2017 Lancet Respir Med 28668356
PMC5558856
28 MS008 Comparison of low- and ultralow-dose computed tomography protocols for quantitative lung and airway assessment. Hammond, Emily ; Sloan, Chelsea ; Newell, John D.; Sieren, Jered P.; Saylor, Melissa ; Vidal, Craig ; Hogue, Shayna ; De Stefano, Frank ; Sieren, Alexa ; Hoffman, Eric A.; Sieren, Jessica C. Reading Center: Radiology (University of Iowa) 2017 Med Phys 28657201
PMC5603212
29 MS089 Lower serum IgA is associated with COPD exacerbation risk in SPIROMICS. Putcha, Nirupama ; Paul, Gabriel G.; Azar, Antoine ; Wise, Robert A.; O'Neal, Wanda K.; Dransfield, Mark T.; Woodruff, Prescott G.; Curtis, Jeffrey L.; Comellas, Alejandro P.; Drummond, Bradley ; Lambert, Allison A.; Paulin, Laura M.; Fawzy, Ashraf ; Kanner, Richard E.; Paine, Robert ; Han, Meilan K.; Martinez, Fernando J.; Bowler, Russell P.; Barr, Graham ; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2018 PLoS One 29649230
PMC5896903
30 MS093 Association of thrombocytosis with COPD morbidity: the SPIROMICS and COPDGene cohorts. Fawzy, Ashraf ; Putcha, Nirupama ; Paulin, Laura M.; Aaron, Carrie P.; Labaki, Wassim W.; Han, Meilan K.; Wise, Robert A.; Kanner, Richard E.; Bowler, Russell P.; Barr, Graham ; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2018 Respir Res 29373977
PMC5787242
31 MS012 Sleep disruption as a predictor of quality of life among patients in the subpopulations and intermediate outcome measures in COPD study (SPIROMICS). Zeidler, Michelle R.; Martin, Jennifer L.; Kleerup, Eric C.; Schneider, Hartmut ; Mitchell, Michael N.; Hansel, Nadia N.; Sundar, Krishna ; Schotland, Helena ; Basner, Robert C.; Wells, Michael ; Krishnan, Jerry A.; Criner, Gerard J.; Cristenson, Stephanie ; Krachman, Samuel ; Badr, Safwan Clinical Center: Los Angeles (University of California at Los Angeles) 2018 Sleep 29534240
PMC5946919
32 MS063 Imaging-based clusters in current smokers of the COPD cohort associate with clinical characteristics: the SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS). Haghighi, Babak ; Choi, Sanghun ; Choi, Jiwoong ; Hoffman, Eric A.; Comellas, Alejandro P.; Newell, John D.; Barr, Graham ; Bleecker, Eugene ; Cooper, Christopher B.; Couper, David ; Han, Mei Lan; Hansel, Nadia N.; Kanner, Richard E.; Kazerooni, Ella A.; Kleerup, Eric A.C.; Martinez, Fernando J.; O'Neal, Wanda ; Rennard, Stephen I.; Woodruff, Prescott G.; Lin, Ching-Long Clinical Center: Iowa (University of Iowa) 2018 Respir Res 30227877
PMC6145340
33 MS082 Mucin Concentrations and Peripheral Airway Obstruction in Chronic Obstructive Pulmonary Disease. Kesimer, Mehmet ; Smith, Benjamin M.; Ceppe, Agathe ; Ford, Amina A.; Anderson, Wayne H.; Barr, Graham ; O'Neal, Wanda K.; Boucher, Richard C. Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2018 Am J Respir Crit Care Med 30130124
PMC6290944
34 MS092 Rural Residence and Chronic Obstructive Pulmonary Disease Exacerbations. Analysis of the SPIROMICS Cohort. Burkes, Robert M.; Gassett, Amanda J.; Ceppe, Agathe S.; Anderson, Wayne ; O'Neal, Wanda K.; Woodruff, Prescott G.; Krishnan, Jerry A.; Barr, Graham ; Han, Meilan K.; Martinez, Fernando J.; Comellas, Alejandro P.; Lambert, Allison A.; Kaufman, Joel D.; Dransfield, Mark T.; Wells, Michael ; Kanner, Richard E.; Paine, Robert ; Bleecker, Eugene R.; Paulin, Laura M.; Hansel, Nadia N.; Drummond, Bradley Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2018 Ann Am Thorac Soc 29584453
PMC6207115
35 MS095 NT-proBNP in stable COPD and future exacerbation risk: Analysis of the SPIROMICS cohort. Labaki, Wassim W.; Xia, Meng ; Murray, Susan ; Curtis, Jeffrey L.; Barr, Graham ; Bhatt, Surya P.; Bleecker, Eugene R.; Hansel, Nadia N.; Cooper, Christopher B.; Dransfield, Mark T.; Wells, Michael ; Hoffman, Eric A.; Kanner, Richard E.; Paine, Robert ; Ortega, Victor E.; Peters, Stephen P.; Krishnan, Jerry A.; Bowler, Russell P.; Couper, David J.; Woodruff, Prescott G.; Martinez, Fernando J.; Martinez, Carlos H.; Han, Meilan K. Clinical Center: Michigan (University of Michigan) 2018 Respir Med 29957287
PMC6084793
36 MS077 Elevated circulating MMP-9 is linked to increased COPD exacerbation risk in SPIROMICS and COPDGene. Wells, Michael ; Parker, Margaret M.; Oster, Robert A.; Bowler, Russ P.; Dransfield, Mark T.; Bhatt, Surya P.; Cho, Michael H.; Kim, Victor ; Curtis, Jeffrey L.; Martinez, Fernando J.; Paine, Robert ; O'Neal, Wanda ; Labaki, Wassim W.; Kaner, Robert J.; Barjaktarevic, Igor ; Han, Meilan K.; Silverman, Edwin K.; Crapo, James D.; Barr, Graham ; Woodruff, Prescott ; Castaldi, Peter J.; Gaggar, Amit Clinical Center: Birmingham (University of Alabama at Birmingham) 2018 JCI Insight 30429371
PMC6302944
37 MS142 Centrilobular emphysema and coronary artery calcification: mediation analysis in the SPIROMICS cohort. Bhatt, Surya P.; Nath, Hrudaya P.; Kim, Young-Il ; Ramachandran, Rekha ; Watts, Jubal R.; Terry, Nina L.J.; Sonavane, Sushil ; Deshmane, Swati P.; Woodruff, Prescott G.; Oelsner, Elizabeth C.; Bodduluri, Sandeep ; Han, Meilan K.; Labaki, Wassim W.; Wells, Michael ; Martinez, Fernando J.; Barr, Graham ; Dransfield, Mark T. Clinical Center: Birmingham (University of Alabama at Birmingham) 2018 Respir Res 30563576
PMC6299495
38 MS073 Genome-wide association study of lung function and clinical implication in heavy smokers. Li, Xingnan ; Ortega, Victor E.; Ampleford, Elizabeth J.; Barr, Graham ; Christenson, Stephanie A.; Cooper, Christopher B.; Couper, David ; Dransfield, Mark T.; Han, Mei Lan K.; Hansel, Nadia N.; Hoffman, Eric A.; Kanner, Richard E.; Kleerup, Eric C.; Martinez, Fernando J.; Paine, Robert ; Woodruff, Prescott G.; Hawkins, Gregory A.; Bleecker, Eugene R.; Meyers, Deborah A. Clinical Center: Tucson (University of Arizona) 2018 BMC Med Genet 30068317
PMC6090900
39 MS080 Alveolar eosinophilia in current smokers with chronic obstructive pulmonary disease in the SPIROMICS cohort. Martinez, Carlos H.; Li, Sara X.; Hirzel, Andrew J.; Stolberg, Valerie R.; Alexis, Neil E.; Barr, Graham ; Bleecker, Eugene R.; Carretta, Elizabeth E.; Christenson, Stephanie A.; Cooper, Christopher B.; Couper, David J.; Doerschuk, Claire M.; Han, Meilan K.; Hansel, Nadia N.; Hastie, Annette T.; Hoffman, Eric A.; Kaner, Robert J.; Martinez, Fernando J.; Meyers, Deborah A.; O'Neal, Wanda K.; Paine, Robert ; Putcha, Nirupama ; Rennard, Stephen I.; Woodruff, Prescott G.; Zeidler, Michelle ; Curtis, Jeffrey L.; Freeman, Christine M. Clinical Center: Michigan (University of Michigan) 2018 J Allergy Clin Immunol 28916185
PMC5758424
40 MS053 Human airway branch variation and chronic obstructive pulmonary disease. Smith, Benjamin M.; Traboulsi, Hussein ; Austin, John H.M.; Manichaikul, Ani ; Hoffman, Eric A.; Bleecker, Eugene R.; Cardoso, Wellington V.; Cooper, Christopher ; Couper, David J.; Dashnaw, Stephen M.; Guo, Jia ; Han, Meilan K.; Hansel, Nadia N.; Hughes, Emlyn W.; Jacobs, David R.; Kanner, Richard E.; Kaufman, Joel D.; Kleerup, Eric ; Lin, Ching-Long ; Liu, Kiang ; Cascio, Christian M.Lo; Martinez, Fernando J.; Nguyen, Jennifer N.; Prince, Martin R.; Rennard, Stephen ; Rich, Stephen S.; Simon, Leora ; Sun, Yanping ; Watson, Karol E.; Woodruff, Prescott G.; Baglole, Carolyn J.; Barr, Graham Clinical Center: New York (Columbia University) 2018 Proc Natl Acad Sci U S A 29339516
PMC5798356
41 MS022 Association between Emphysema and Chronic Obstructive Pulmonary Disease Outcomes in the COPDGene and SPIROMICS Cohorts: A Post Hoc Analysis of Two Clinical Trials. Han, Meilan K.; Tayob, Nabihah ; Murray, Susan ; Woodruff, Prescott G.; Curtis, Jeffrey L.; Kim, Victor ; Criner, Gerard ; Galbán, Craig J.; Ross, Brian D.; Hoffman, Eric A.; Lynch, David A.; Kazerooni, Ella ; Martinez, Fernando J. Clinical Center: Michigan (University of Michigan) 2018 Am J Respir Crit Care Med 29485901
PMC6058986
42 MS087 Occupational Exposures and Computed Tomographic Imaging Characteristics in the SPIROMICS Cohort. Paulin, Laura M.; Smith, Benjamin M.; Koch, Abby ; Han, MeiLan ; Hoffman, Eric A.; Martinez, Carlos ; Ejike, Chinedu ; Blanc, Paul D.; Rous, Jennifer ; Barr, Graham ; Peters, Stephen P.; Paine, Robert ; Pirozzi, Cheryl ; Cooper, Christopher B.; Dransfield, Mark T.; Comellas, Alejandro P.; Kanner, Richard E.; Drummond, Brad ; Putcha, Nirupama ; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2018 Ann Am Thorac Soc 30339479
PMC6322018
43 MS041 Heterogeneous burden of lung disease in smokers with borderline airflow obstruction. Pirozzi, Cheryl S.; Gu, Tian ; Quibrera, Pedro M.; Carretta, Elizabeth E.; Han, Meilan K.; Murray, Susan ; Cooper, Christopher B.; Tashkin, Donald P.; Kleerup, Eric C.; Barjaktarevic, Igor ; Hoffman, Eric A.; Martinez, Carlos H.; Christenson, Stephanie A.; Hansel, Nadia N.; Barr, Graham ; Bleecker, Eugene R.; Ortega, Victor E.; Martinez, Fernando J.; Kanner, Richard E.; Paine, Robert Clinical Center: Utah (University of Utah) 2018 Respir Res 30454050
PMC6245799
44 MS119 A Genetic Risk Score Associated with Chronic Obstructive Pulmonary Disease Susceptibility and Lung Structure on Computed Tomography. Oelsner, Elizabeth C.; Ortega, Victor E.; Smith, Benjamin M.; Nguyen, Jennifer N.; Manichaikul, Ani W.; Hoffman, Eric A.; Guo, Xiuqing ; Taylor, Kent D.; Woodruff, Prescott G.; Couper, David J.; Hansel, Nadia N.; Martinez, Fernando J.; Paine, Robert ; Han, Meilan K.; Cooper, Christopher ; Dransfield, Mark T.; Criner, Gerard ; Krishnan, Jerry A.; Bowler, Russell ; Bleecker, Eugene R.; Peters, Stephen ; Rich, Stephen S.; Meyers, Deborah A.; Rotter, Jerome I.; Barr, Graham Clinical Center: New York (Columbia University) 2019 Am J Respir Crit Care Med 30925230
PMC6775892
45 MS144 Radiographic lung volumes predict progression to COPD in smokers with preserved spirometry in SPIROMICS. Arjomandi, Mehrdad ; Zeng, Siyang ; Barjaktarevic, Igor ; Barr, Graham ; Bleecker, Eugene R.; Bowler, Russell P.; Buhr, Russell G.; Criner, Gerard J.; Comellas, Alejandro P.; Cooper, Christopher B.; Couper, David J.; Curtis, Jeffrey L.; Dransfield, Mark T.; Han, Meilan K.; Hansel, Nadia N.; Hoffman, Eric A.; Kaner, Robert J.; Kanner, Richard E.; Krishnan, Jerry A.; Paine, Robert ; Peters, Stephen P.; Rennard, Stephen I.; Woodruff, Prescott G. Clinical Center: San Francisco (University of California at San Francisco) 2019 Eur Respir J 31439683
PMC7089627
46 MS113 Chronic lung disease in adult recurrent tuberculosis survivors in Zimbabwe: a cohort study. Chin, A T.; Rylance, J ; Makumbirofa, S ; Meffert, S ; Vu, T ; Clayton, J ; Mason, P ; Woodruff, P ; Metcalfe, J Clinical Center: San Francisco (University of California at San Francisco) 2019 Int J Tuberc Lung Dis 30808453
PMC6860915
47 MS198 The matrikine acetyl-proline-glycine-proline and clinical features of COPD: findings from SPIROMICS. Wells, Michael ; Xing, Dongqi ; Viera, Liliana ; Burkes, Robert M.; Wu, Yixin ; Bhatt, Surya P.; Dransfield, Mark T.; Couper, David J.; O'Neal, Wanda ; Hoffman, Eric A.; Gaggar, Amit ; Barjaktarevic, Igor ; Curtis, Jeffrey L.; Labaki, Wassim W.; Han, Mei Lan K.; Freeman, Christine M.; Putcha, Nirupama ; Schlange, Thomas ; Blalock, Edwin Clinical Center: Birmingham (University of Alabama at Birmingham) 2019 Respir Res 31718676
PMC6852714
48 MS081 An airway epithelial IL-17A response signature identifies a steroid-unresponsive COPD patient subgroup. Christenson, Stephanie A.; van den Berge, Maarten ; Faiz, Alen ; Inkamp, Kai ; Bhakta, Nirav ; Bonser, Luke R.; Zlock, Lorna T.; Barjaktarevic, Igor Z.; Barr, Graham ; Bleecker, Eugene R.; Boucher, Richard C.; Bowler, Russell P.; Comellas, Alejandro P.; Curtis, Jeffrey L.; Han, Meilan K.; Hansel, Nadia N.; Hiemstra, Pieter S.; Kaner, Robert J.; Krishnanm, Jerry A.; Martinez, Fernando J.; O'Neal, Wanda K.; Paine, Robert ; Timens, Wim ; Wells, Michael ; Spira, Avrum ; Erle, David J.; Woodruff, Prescott G. Clinical Center: San Francisco (University of California at San Francisco) 2019 J Clin Invest 30383540
PMC6307967
49 MS112 Aspirin Use and Respiratory Morbidity in COPD: A Propensity Score-Matched Analysis in Subpopulations and Intermediate Outcome Measures in COPD Study. Fawzy, Ashraf ; Putcha, Nirupama ; Aaron, Carrie P.; Bowler, Russell P.; Comellas, Alejandro P.; Cooper, Christopher B.; Dransfield, Mark T.; Han, Meilan K.; Hoffman, Eric A.; Kanner, Richard E.; Krishnan, Jerry A.; Labaki, Wassim W.; Paine, Robert ; Paulin, Laura M.; Peters, Stephen P.; Wise, Robert ; Barr, Graham ; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2019 Chest 30593776
PMC6414789
50 MS181 Elastin-Specific Autoimmunity in Smokers With Thoracic Aortic Aneurysm and Dissection is Independent of Chronic Obstructive Pulmonary Disease. Gu, Bon-Hee ; Choi, Justin C.; Shen, Ying H.; Song, Li-Zhen ; Scheurer, Michael E.; Luong, Amber ; Rodriguez, Antony ; Woodruff, Prescott ; Koth, Laura ; Corry, David B.; Kheradmand, Farrah ; LeMaire, Scott A. Clinical Center: San Francisco (University of California at San Francisco) 2019 J Am Heart Assoc 30957625
PMC6507218
51 MS145 Serum amino acid concentrations and clinical outcomes in smokers: SPIROMICS metabolomics study. Labaki, Wassim W.; Gu, Tian ; Murray, Susan ; Curtis, Jeffrey L.; Yeomans, Larisa ; Bowler, Russell P.; Barr, Graham ; Comellas, Alejandro P.; Hansel, Nadia N.; Cooper, Christopher B.; Barjaktarevic, Igor ; Kanner, Richard E.; Paine, Robert ; McDonald, Merry-Lynn N.; Krishnan, Jerry A.; Peters, Stephen P.; Woodruff, Prescott G.; O'Neal, Wanda K.; Diao, Wenqi ; He, Bei ; Martinez, Fernando J.; Standiford, Theodore J.; Stringer, Kathleen A.; Han, Meilan K. Clinical Center: Michigan (University of Michigan) 2019 Sci Rep 31388056
PMC6684630
52 MS122 Safety and Tolerability of Comprehensive Research Bronchoscopy in Chronic Obstructive Pulmonary Disease. Results from the SPIROMICS Bronchoscopy Substudy. Wells, Michael ; Arenberg, Douglas A.; Barjaktarevic, Igor ; Bhatt, Surya P.; Bowler, Russell P.; Christenson, Stephanie A.; Couper, David J.; Dransfield, Mark T.; Han, Meilan K.; Hoffman, Eric A.; Kaner, Robert J.; Kim, Victor ; Kleerup, Eric ; Martinez, Fernando J.; Moore, Wendy C.; O'Beirne, Sarah L.; Paine, Robert ; Putcha, Nirupama ; Raman, Sanjeev M.; Barr, Graham ; Rennard, Stephen I.; Woodruff, Prescott G.; Curtis, Jeffrey L. Clinical Center: Birmingham (University of Alabama at Birmingham) 2019 Ann Am Thorac Soc 30653926
PMC6441692
53 MS146 Systemic Markers of Inflammation in Smokers With Symptoms Despite Preserved Spirometry in SPIROMICS. Garudadri, Suresh ; Woodruff, Prescott G.; Han, Meilan K.; Curtis, Jeffrey L.; Barr, Graham ; Bleecker, Eugene R.; Bowler, Russell P.; Comellas, Alejandro ; Cooper, Christopher B.; Criner, Gerard ; Dransfield, Mark T.; Hansel, Nadia N.; Paine, Robert ; Krishnan, Jerry A.; Peters, Stephen P.; Hastie, Annette T.; Martinez, Fernando J.; O'Neal, Wanda K.; Couper, David J.; Alexis, Neil E.; Christenson, Stephanie A. Clinical Center: San Francisco (University of California at San Francisco) 2019 Chest 30684474
PMC6533449
54 MS203 Bronchoalveolar Lavage Fluid from COPD Patients Reveals More Compounds Associated with Disease than Matched Plasma. Halper-Stromberg, Eitan ; Gillenwater, Lucas ; Cruickshank-Quinn, Charmion ; O'Neal, Wanda Kay; Reisdorph, Nichole ; Petrache, Irina ; Zhuang, Yonghua ; Labaki, Wassim W.; Curtis, Jeffrey L.; Wells, James ; Rennard, Stephen ; Pratte, Katherine A.; Woodruff, Prescott ; Stringer, Kathleen A.; Kechris, Katerina ; Bowler, Russell P. Clinical Center: Denver (National Jewish Health) 2019 Metabolites 31349744
PMC6724137
55 MS006 Clinical Significance of Bronchodilator Responsiveness Evaluated by Forced Vital Capacity in COPD: SPIROMICS Cohort Analysis. Barjaktarevic, Igor Z.; Buhr, Russell G.; Wang, Xiaoyan ; Hu, Scott ; Couper, David ; Anderson, Wayne ; Kanner, Richard E.; Iii, Robert Paine; Bhatt, Surya P.; Bhakta, Nirav R.; Arjomandi, Mehrdad ; Kaner, Robert J.; Pirozzi, Cheryl S.; Curtis, Jeffrey L.; O'Neal, Wanda K.; Woodruff, Prescott G.; Han, Meilan K.; Martinez, Fernando J.; Hansel, Nadia ; Wells, James Michael; Ortega, Victor E.; Hoffman, Eric A.; Doerschuk, Claire M.; Kim, Victor ; Dransfield, Mark T.; Drummond, Bradley ; Bowler, Russell ; Criner, Gerard ; Christenson, Stephanie A.; Ronish, Bonnie ; Peters, Stephen P.; Krishnan, Jerry A.; Tashkin, Donald P.; Cooper, Christopher B. Clinical Center: Los Angeles (University of California at Los Angeles) 2019 Int J Chron Obstruct Pulmon Dis 31908441
PMC6930016
56 MS094 Alignment of Inhaled Chronic Obstructive Pulmonary Disease Therapies with Published Strategies. Analysis of the Global Initiative for Chronic Obstructive Lung Disease Recommendations in SPIROMICS. Ghosh, Sohini ; Anderson, Wayne H.; Putcha, Nirupama ; Han, Meilan K.; Curtis, Jeffrey L.; Criner, Gerard J.; Dransfield, Mark T.; Barr, Graham ; Krishnan, Jerry A.; Lazarus, Stephen C.; Cooper, Christopher B.; Paine, Robert ; Peters, Stephen P.; Hansel, Nadia N.; Martinez, Fernando J.; Drummond, Bradley Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2019 Ann Am Thorac Soc 30216731
PMC6376942
57 MS038 Novel Respiratory Disability Score Predicts COPD Exacerbations and Mortality in the SPIROMICS Cohort. Cooper, Christopher B.; Paine, Robert ; Curtis, Jeffrey L.; Kanner, Richard E.; Martinez, Carlos H.; Meldrum, Catherine A.; Bowler, Russell ; O'Neal, Wanda ; Hoffman, Eric A.; Couper, David ; Quibrera, Miguel ; Criner, Gerald ; Dransfield, Mark T.; Han, Meilan K.; Hansel, Nadia N.; Krishnan, Jerry A.; Lazarus, Stephen C.; Peters, Stephen P.; Barr, Graham ; Martinez, Fernando J.; Woodruff, Prescott G. Clinical Center: Los Angeles (University of California at Los Angeles) 2020 Int J Chron Obstruct Pulmon Dis 32821092
PMC7417644
58 MS116 Plasma Cathelicidin is Independently Associated with Reduced Lung Function in COPD: Analysis of the Subpopulations and Intermediate Outcome Measures in COPD Study Cohort. Burkes, Robert M.; Ceppe, Agathe S.; Couper, David J.; Comellas, Alejandro P.; Wells, Michael ; Peters, Stephen P.; Criner, Gerard J.; Kanner, Richard E.; Paine, Robert ; Christenson, Stephanie A.; Cooper, Christopher B.; Barjaktarevic, Igor Z.; Krishnan, Jerry A.; Labaki, Wassim W.; Han, Meilan K.; Curtis, Jeffrey L.; Hansel, Nadia N.; Wise, Robert A.; Drummond, Bradley Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2020 Chronic Obstr Pulm Dis 33108110
PMC7883905
59 MS207 A Risk Prediction Model for Mortality Among Smokers in the COPDGene® Study. Strand, Matthew ; Austin, Erin ; Moll, Matthew ; Pratte, Katherine A.; Regan, Elizabeth A.; Hayden, Lystra P.; Bhatt, Surya P.; Boriek, Aladin M.; Casaburi, Richard ; Silverman, Edwin K.; Fortis, Spyridon ; Ruczinski, Ingo ; Koegler, Harald ; Rossiter, Harry B.; Occhipinti, Mariaelena ; Hanania, Nicola A.; Gebrekristos, Hirut T.; Lynch, David A.; Kunisaki, Ken M.; Young, Kendra A.; Sieren, Jessica C.; Ragland, Margaret ; Hokanson, John E.; Lutz, Sharon M.; Make, Barry J.; Kinney, Gregory L.; Cho, Michael H.; Pistolesi, Massimo ; DeMeo, Dawn L.; Sciurba, Frank C.; Comellas, Alejandro P.; Diaz, Alejandro A.; Barjaktarevic, Igor ; Bowler, Russell P.; Kanner, Richard E.; Peters, Stephen P.; Ortega, Victor E.; Dransfield, Mark T.; Crapo, James D. Clinical Center: Denver (National Jewish Health) 2020 Chronic Obstr Pulm Dis 32877963
PMC7883903
60 MS159 Association of Dysanapsis With Chronic Obstructive Pulmonary Disease Among Older Adults Smith, Benjamin M.; Kirby, Miranda ; Hoffman, Eric A.; Kronmal, Richard A.; Aaron, Shawn D.; Allen, Norrina B.; Bertoni, Alain ; Coxson, Harvey O.; Cooper, Chris ; Couper, David J.; Criner, Gerard ; Dransfield, Mark T.; Han, Meilan K.; Hansel, Nadia N.; Jacobs, David R.; Kaufman, Joel D.; Lin, Ching-Long ; Manichaikul, Ani ; Martinez, Fernando J.; Michos, Erin D.; Oelsner, Elizabeth C.; Paine, Robert ; Watson, Karol E.; Benedetti, Andrea ; Tan, Wan C.; Bourbeau, Jean ; Woodruff, Prescott G.; Barr, Graham Clinical Center: New York (Columbia University) 2020 JAMA 32515814
PMC7284296
61 MS023 The Effects of Rare Variants on Lung Function and Emphysema in SPIROMICS. Ortega, Victor E.; Li, Xingnan ; O'Neal, Wanda K.; Lackey, Lela ; Ampleford, Elizabeth ; Hawkins, Gregory A.; Grayeski, Philip J.; Laederach, Alain ; Barjaktarevic, Igor ; Barr, Graham ; Cooper, Christopher ; Couper, David ; Han, Meilan K.; Kanner, Richard E.; Kleerup, Eric C.; Martinez, Fernando J.; Paine, Robert ; Peters, Stephen P.; Pirozzi, Cheryl ; Rennard, Stephen I.; Woodruff, Prescott G.; Hoffman, Eric A.; Meyers, Deborah A.; Bleecker, Eugene R. Clinical Center: Winston-Salem (Wake Forest University Health Sciences) 2020 Am J Respir Crit Care Med 31661293
PMC7047460
62 MS158 Associations Among 25-Hydroxyvitamin D Levels, Lung Function, and Exacerbation Outcomes in COPD: An Analysis of the SPIROMICS Cohort. Burkes, Robert M.; Ceppe, Agathe S.; Doerschuk, Claire M.; Couper, David ; Hoffman, Eric A.; Comellas, Alejandro P.; Barr, Graham ; Krishnan, Jerry A.; Cooper, Christopher ; Labaki, Wassim W.; Ortega, Victor E.; Wells, Michael ; Criner, Gerard J.; Woodruff, Prescott G.; Bowler, Russell P.; Pirozzi, Cheryl S.; Hansel, Nadia N.; Wise, Robert A.; Brown, Todd T.; Drummond, Bradley Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2020 Chest 31958447
PMC7118244
63 MS085 Current smoking with or without chronic bronchitis is independently associated with goblet cell hyperplasia in healthy smokers and COPD subjects. Kim, Victor ; Jeong, Stephanie ; Zhao, Huaqing ; Kesimer, Mehmet ; Boucher, Richard C.; Wells, Michael ; Christenson, Stephanie A.; Han, Meilan K.; Dransfield, Mark ; Paine, Robert ; Cooper, Christopher B.; Barjaktarevic, Igor ; Bowler, Russell ; Curtis, Jeffrey L.; Kaner, Robert J.; O'Beirne, Sarah L.; O'Neal, Wanda K.; Rennard, Stephen I.; Martinez, Fernando J.; Woodruff, Prescott G. Clinical Center: Pennsylvania (Temple University) 2020 Sci Rep 33208859
PMC7674445
64 MS194 Association of urine mitochondrial DNA with clinical measures of COPD in the SPIROMICS cohort Zhang, William Z.; Rice, Michelle C.; Hoffman, Katherine L.; Oromendia, Clara ; Barjaktarevic, Igor Z.; Wells, Michael ; Hastie, Annette T.; Labaki, Wassim W.; Cooper, Christopher B.; Comellas, Alejandro P.; Criner, Gerard J.; Krishnan, Jerry A.; Paine, Robert ; Hansel, Nadia N.; Bowler, Russell P.; Barr, Graham ; Peters, Stephen P.; Woodruff, Prescott G.; Curtis, Jeffrey L.; Han, Meilan K.; Ballman, Karla V.; Martinez, Fernando J.; Choi, Augustine Mk; Nakahira, Kiichi ; Cloonan, Suzanne M.; Choi, Mary E. Weill Cornell Medical Center 2020 JCI Insight 31895696
PMC7098791
65 MS121 Association of Long-term Ambient Ozone Exposure With Respiratory Morbidity in Smokers. Paulin, Laura M.; Gassett, Amanda J.; Alexis, Neil E.; Kirwa, Kipruto ; Kanner, Richard E.; Peters, Stephen ; Krishnan, Jerry A.; Paine, Robert ; Dransfield, Mark ; Woodruff, Prescott G.; Cooper, Christopher B.; Barr, Graham ; Comellas, Alejandro P.; Pirozzi, Cheryl S.; Han, MeiLan ; Hoffman, Eric A.; Martinez, Fernando J.; Woo, Han ; Peng, Roger D.; Fawzy, Ashraf ; Putcha, Nirupama ; Breysse, Patrick N.; Kaufman, Joel D.; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2020 JAMA Intern Med 31816012
PMC6902160
66 MS170 Increased airway iron parameters and risk for exacerbation in COPD: an analysis from SPIROMICS. Zhang, William Z.; Oromendia, Clara ; Kikkers, Sarah Ann; Butler, James J.; O'Beirne, Sarah ; Kim, Kihwan ; O'Neal, Wanda K.; Freeman, Christine M.; Christenson, Stephanie A.; Peters, Stephen P.; Wells, Michael ; Doerschuk, Claire ; Putcha, Nirupama ; Barjaktarevic, Igor ; Woodruff, Prescott G.; Cooper, Christopher B.; Bowler, Russell P.; Comellas, Alejandro P.; Criner, Gerard J.; Paine, Robert ; Hansel, Nadia N.; Han, Meilan K.; Crystal, Ronald G.; Kaner, Robert J.; Ballman, Karla V.; Curtis, Jeffrey L.; Martinez, Fernando J.; Cloonan, Suzanne M. Weill Cornell Medical Center 2020 Sci Rep 32601308
PMC7324559
67 MS192 Defining Chronic Mucus Hypersecretion Using the CAT in the SPIROMICS Cohort. Stott-Miller, Marni ; Müllerová, Hana ; Miller, Bruce ; Tabberer, Maggie ; Baou, Céline El; Keeley, Tom ; Martinez, Fernando J.; Han, MeiLan ; Dransfield, Mark ; Hansel, Nadia N.; Cooper, Christopher B.; Woodruff, Prescott ; Ortega, Victor E.; Comellas, Alejandro P.; Iii, Robert Paine; Kanner, Richard E.; Anderson, Wayne ; Drummond, Bradley ; Kim, Victor ; Tal-Singer, Ruth ; Lazaar, Aili L. 2020 Int J Chron Obstruct Pulmon Dis 33116463
PMC7568676
68 MS205 Plasma Metabolomic Signatures of Chronic Obstructive Pulmonary Disease and the Impact of Genetic Variants on Phenotype-Driven Modules. Gillenwater, Lucas A.; Pratte, Katherine A.; Hobbs, Brian D.; Cho, Michael H.; Zhuang, Yonghua ; Halper-Stromberg, Eitan ; Cruickshank-Quinn, Charmion ; Reisdorph, Nichole ; Petrache, Irina ; Labaki, Wassim W.; O'Neal, Wanda K.; Ortega, Victor E.; Jones, Dean P.; Uppal, Karan ; Jacobson, Sean ; Michelotti, Gregory ; Wendt, Christine H.; Kechris, Katerina J.; Bowler, Russell P. Clinical Center: Denver (National Jewish Health) 2020 Netw Syst Med 33987620
PMC8109053
69 MS194 Association of plasma mitochondrial DNA with COPD severity and progression in the SPIROMICS cohort. Zhang, William Z.; Hoffman, Katherine L.; Schiffer, Kristen T.; Oromendia, Clara ; Rice, Michelle C.; Barjaktarevic, Igor ; Peters, Stephen P.; Putcha, Nirupama ; Bowler, Russell P.; Wells, Michael ; Couper, David J.; Labaki, Wassim W.; Curtis, Jeffrey L.; Han, Meilan K.; Paine, Robert ; Woodruff, Prescott G.; Criner, Gerard J.; Hansel, Nadia N.; Diaz, Ivan ; Ballman, Karla V.; Nakahira, Kiichi ; Choi, Mary E.; Martinez, Fernando J.; Choi, Augustine M.K.; Cloonan, Suzanne M. Weill Cornell Medical Center 2021 Respir Res 33902556
PMC8074408
70 MS162 Lung microbiota associations with clinical features of COPD in the SPIROMICS cohort. Opron, Kristopher ; Begley, Lesa A.; Erb-Downward, John R.; Freeman, Christine ; Madapoosi, Siddharth ; Alexis, Neil E.; Barjaktarevic, Igor ; Barr, Graham ; Bleecker, Eugene R.; Bowler, Russell P.; Christenson, Stephanie A.; Comellas, Alejandro P.; Cooper, Christopher B.; Couper, David J.; Doerschuk, Claire M.; Dransfield, Mark T.; Han, Meilan K.; Hansel, Nadia N.; Hastie, Annette T.; Hoffman, Eric A.; Kaner, Robert J.; Krishnan, Jerry ; O'Neal, Wanda K.; Ortega, Victor E.; Paine, Robert ; Peters, Stephen P.; Wells, Michael ; Woodruff, Prescott G.; Martinez, Fernando J.; Curtis, Jeffrey L.; Huffnagle, Gary B.; Huang, Yvonne J. Clinical Center: Michigan (University of Michigan) 2021 NPJ Biofilms Microbiomes 33547327
PMC7865064
71 MS125 The influence of social support on COPD outcomes mediated by depression. Turnier, Leonard ; Eakin, Michelle ; Woo, Han ; Dransfield, Mark ; Parekh, Trisha ; Krishnan, Jerry A.; Kanner, Richard ; Cooper, Christopher B.; Woodruff, Prescott G.; Wise, Robert ; Han, Meilan K.; Romero, Karina ; Paulin, Laura M.; Peters, Stephen ; Drummond, Brad ; Bleecker, Eugene R.; Bowler, Russell ; Comellas, Alejandro P.; Couper, David ; Paine, Robert ; Martinez, Fernando ; Barr, Graham ; Putcha, Nirupama ; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2021 PLoS One 33730034
PMC7968645
72 MS219 Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort. Radicioni, Giorgia ; Ceppe, Agathe ; Ford, Amina A.; Alexis, Neil E.; Barr, Graham ; Bleecker, Eugene R.; Christenson, Stephanie A.; Cooper, Christopher B.; Han, Meilan K.; Hansel, Nadia N.; Hastie, Annette T.; Hoffman, Eric A.; Kanner, Richard E.; Martinez, Fernando J.; Ozkan, Esin ; Paine, Robert ; Woodruff, Prescott G.; O'Neal, Wanda K.; Boucher, Richard C.; Kesimer, Mehmet Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2021 Lancet Respir Med 34058148
PMC8570975
73 MS156 Modeling residential indoor concentrations of PM , NO , NO , and secondhand smoke in the Subpopulations and Intermediate Outcome Measures in COPD (SPIROMICS) Air study. Zusman, Marina ; Gassett, Amanda J.; Kirwa, Kipruto ; Barr, Graham ; Cooper, Christopher B.; Han, Meilan K.; Kanner, Richard E.; Koehler, Kirsten ; Ortega, Victor E.; Rd, Robert Paine; Paulin, Laura ; Pirozzi, Cheryl ; Rule, Ana ; Hansel, Nadia N.; Kaufman, Joel D. 2021 Indoor Air 33037695
PMC8202242
74 MS190 Defining Resilience to Smoking-related Lung Disease: A Modified Delphi Approach from SPIROMICS. Oh, Anita L.; Mularski, Richard A.; Barjaktarevic, Igor ; Barr, Graham ; Bowler, Russell P.; Comellas, Alejandro P.; Cooper, Christopher B.; Criner, Gerard J.; Han, Meilan K.; Hansel, Nadia N.; Hoffman, Eric A.; Kanner, Richard E.; Krishnan, Jerry A.; Paine, Robert ; Parekh, Trisha M.; Peters, Stephen P.; Christenson, Stephanie A.; Woodruff, Prescott G. Clinical Center: San Francisco (University of California at San Francisco) 2021 Ann Am Thorac Soc 33631079
PMC8641833
75 MS242 Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium. Kasela, Silva ; Ortega, Victor E.; Martorella, Molly ; Garudadri, Suresh ; Nguyen, Jenna ; Ampleford, Elizabeth ; Pasanen, Anu ; Nerella, Srilaxmi ; Buschur, Kristina L.; Barjaktarevic, Igor Z.; Barr, Graham ; Bleecker, Eugene R.; Bowler, Russell P.; Comellas, Alejandro P.; Cooper, Christopher B.; Couper, David J.; Criner, Gerard J.; Curtis, Jeffrey L.; Han, Meilan K.; Hansel, Nadia N.; Hoffman, Eric A.; Kaner, Robert J.; Krishnan, Jerry A.; Martinez, Fernando J.; McDonald, Merry-Lynn N.; Meyers, Deborah A.; Paine, Robert ; Peters, Stephen P.; Castro, Mario ; Denlinger, Loren C.; Erzurum, Serpil C.; Fahy, John V.; Israel, Elliot ; Jarjour, Nizar N.; Levy, Bruce D.; Li, Xingnan ; Moore, Wendy C.; Wenzel, Sally E.; Zein, Joe ; Langelier, Charles ; Woodruff, Prescott G.; Lappalainen, Tuuli ; Christenson, Stephanie A. Clinical Center: San Francisco (University of California at San Francisco) 2021 Genome Med 33883027
PMC8059115
76 MS158 Age-Dependent Associations Between 25-Hydroxy Vitamin D Levels and COPD Symptoms: Analysis of SPIROMICS. Burkes, Robert M.; Couper, David J.; Barjaktarevic, Igor Z.; Cooper, Christopher B.; Labaki, Wassim W.; Han, Meilan K.; Woodruff, Prescott G.; Lazarus, Stephen C.; Parekh, Trisha M.; Paine, Robert ; Comellas, Alejandro P.; Bowler, Russell P.; Loehr, Laura R.; Putcha, Nirupama ; Wise, Robert A.; Brown, Todd T.; Drummond, Bradley Genomics and Informatics Center (University of North Carolina at Chapel Hill) 2021 Chronic Obstr Pulm Dis 33829714
PMC8237982
77 MS178 Contribution of Individual and Neighborhood Factors to Racial Disparities in Respiratory Outcomes. Ejike, Chinedu O.; Woo, Han ; Galiatsatos, Panagis ; Paulin, Laura M.; Krishnan, Jerry A.; Cooper, Christopher B.; Couper, David J.; Kanner, Richard E.; Bowler, Russell P.; Hoffman, Eric A.; Comellas, Alejandro P.; Criner, Gerard J.; Barr, Graham ; Martinez, Fernando J.; Han, Meilan K.; Martinez, Carlos H.; Ortega, Victor E.; Parekh, Trisha M.; Christenson, Stephanie A.; Thakur, Neeta ; Baugh, Aaron ; Belz, Daniel C.; Raju, Sarath ; Gassett, Amanda J.; Kaufman, Joel D.; Putcha, Nirupama ; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2021 Am J Respir Crit Care Med 33007162
PMC8048743
78 MS191 Ratio of FEV/Slow Vital Capacity of < 0.7 Is Associated With Clinical, Functional, and Radiologic Features of Obstructive Lung Disease in Smokers With Preserved Lung Function. Fortis, Spyridon ; Comellas, Alejandro P.; Bhatt, Surya P.; Hoffman, Eric A.; Han, Meilan K.; Bhakta, Nirav R.; Paine, Robert ; Ronish, Bonnie ; Kanner, Richard E.; Dransfield, Mark ; Hoesterey, Daniel ; Buhr, Russell G.; Barr, Graham ; Dolezal, Brett ; Ortega, Victor E.; Drummond, Bradley ; Arjomandi, Mehrdad ; Kaner, Robert J.; Kim, Victor ; Curtis, Jeffrey L.; Bowler, Russell P.; Martinez, Fernando ; Labaki, Wassim W.; Cooper, Christopher B.; O'Neal, Wanda K.; Criner, Gerald ; Hansel, Nadia N.; Krishnan, Jerry A.; Woodruff, Prescott ; Couper, David ; Tashkin, Donald ; Barjaktarevic, Igor Clinical Center: Iowa (University of Iowa) 2021 Chest 33539837
PMC8295909
79 MS200 Latent traits of lung tissue patterns in former smokers derived by dual channel deep learning in computed tomography images. Li, Frank ; Choi, Jiwoong ; Zou, Chunrui ; Newell, John D.; Comellas, Alejandro P.; Lee, Chang Hyun; Ko, Hongseok ; Barr, Graham ; Bleecker, Eugene R.; Cooper, Christopher B.; Abtin, Fereidoun ; Barjaktarevic, Igor ; Couper, David ; Han, MeiLan ; Hansel, Nadia N.; Kanner, Richard E.; Paine, Robert ; Kazerooni, Ella A.; Martinez, Fernando J.; O'Neal, Wanda ; Rennard, Stephen I.; Smith, Benjamin M.; Woodruff, Prescott G.; Hoffman, Eric A.; Lin, Ching-Long Clinical Center: Iowa (University of Iowa) 2021 Sci Rep 33649381
PMC7921389
80 MS261 PLOSL: Population learning followed by one shot learning pulmonary image registration using tissue volume preserving and vesselness constraints Wang, Di ; Pan, Yue ; Durumeric, Oguz C.; Reinhardt, Joseph M.; Hoffman, Eric A.; Schroeder, Joyce D.; Christensen, Gary E. Reading Center: Radiology (University of Iowa) 2022 Med Image Anal 35430476
81 MS168 Significance of FEV 3/FEV 6 in Recognition of Early Airway Disease in Smokers at Risk of Development of COPD: Analysis of the SPIROMICS Cohort Yee, Nathan ; Markovic, Daniela ; Buhr, Russell G.; Fortis, Spyridon ; Arjomandi, Mehrdad ; Couper, David ; Anderson, Wayne H.; Paine, Robert ; Woodruff, Prescott G.; Han, Meilan K.; Martinez, Fernando J.; Barr, Graham ; Wells, James M.; Ortega, Victor E.; Hoffman, Eric A.; Kim, Victor ; Drummond, Bradley ; Bowler, Russell P.; Curtis, Jeffrey L.; Cooper, Christopher B.; Tashkin, Donald P.; Barjaktarevic, Igor Z. Clinical Center: Los Angeles (University of California at Los Angeles) 2022 Chest 34767825
PMC9005864
82 MS163 Reversible Airflow Obstruction Predicts Future COPD Development in the SPIROMICS Cohort Buhr, Russell G.; Barjaktarevic, Igor Z.; Quibrera, Miguel ; Bateman, Lori A.; Bleecker, Eugene R.; Couper, David J.; Curtis, Jeffrey L.; Dolezal, Brett A.; Han, Meilan K.; Hansel, Nadia N.; Krishnan, Jerry A.; Martinez, Fernando J.; McKleroy, William ; Iii, Robert Paine; Rennard, Stephen I.; Tashkin, Donald P.; Woodruff, Prescott G.; Kanner, Richard E.; Cooper, Christopher B. Clinical Center: Los Angeles (University of California at Los Angeles) 2022 Am J Respir Crit Care Med 35549640
83 MS246 A Metabolomic Severity Score for Airflow Obstruction and Emphysema. Godbole, Suneeta ; Labaki, Wassim W.; Pratte, Katherine A.; Hill, Andrew ; Moll, Matthew ; Hastie, Annette T.; Peters, Stephen P.; Gregory, Andrew ; Ortega, Victor E.; Demeo, Dawn ; Cho, Michael H.; Bhatt, Surya P.; Wells, Michael ; Barjaktarevic, Igor ; Stringer, Kathleen A.; Comellas, Alejandro ; O'Neal, Wanda ; Kechris, Katerina ; Bowler, Russell P. Clinical Center: Denver (National Jewish Health) 2022 Metabolites 35629872
PMC9143560
84 MS174 Comparative Impact of Depressive Symptoms and FEV% on Chronic Obstructive Pulmonary Disease. O'Toole, Jacqueline ; Woo, Han ; Putcha, Nirupama ; Cooper, Christopher B.; Woodruff, Prescott ; Kanner, Richard E.; Paine, Robert ; Bowler, Russell P.; Comellas, Alejandro ; Hoth, Karin F.; Krishnan, Jerry A.; Han, MeiLan ; Dransfield, Mark ; Iyer, Anand S.; Couper, David ; Peters, Stephen P.; Criner, Gerard ; Kim, Victor ; Barr, Graham ; Martinez, Fernando J.; Hansel, Nadia N.; Eakin, Michelle N. Clinical Center: Baltimore (Johns Hopkins University) 2022 Ann Am Thorac Soc 34410883
PMC8867359
85 MS074 Clinically Significant and Comorbid Anxiety and Depression Symptoms Predict Severe Respiratory Exacerbations in Smokers: A Post Hoc Analysis of the COPDGene and SPIROMICS Cohorts Iyer, Anand S.; Parekh, Trisha M.; O'Toole, Jacqueline ; Bhatt, Surya P.; Eakin, Michelle N.; Krishnan, Jerry A.; Yohannes, Abebaw M.; Woodruff, Prescott G.; Cooper, Christopher B.; Kanner, Richard E.; Hanania, Nicola A.; Dransfield, Mark T.; Regan, Elizabeth A.; Hoth, Karin F.; Kim, Victor Clinical Center: Pennsylvania (Temple University) 2022 Ann Am Thorac Soc 34343034
86 MS209 Lung Microbiota and Metabolites Collectively Associate with Clinical Outcomes in Milder Stage COPD Madapoosi, Siddharth S.; Cruickshank-Quinn, Charmion ; Opron, Kristopher ; Erb-Downward, John R.; Begley, Lesa A.; Li, Gen ; Barjaktarevic, Igor ; Barr, Graham ; Comellas, Alejandro P.; Couper, David ; Cooper, Christopher B.; Freeman, Christine ; Han, MeiLan ; Kaner, Robert J.; Labaki, Wassim ; Martinez, Fernando J.; Ortega, Victor E.; Peters, Stephen P.; Paine, Robert ; Woodruff, Prescott ; Curtis, Jeffrey L.; Huffnagle, Gary B.; Stringer, Kathleen A.; Bowler, Russell P.; Esther, Charles R.; Reisdorph, Nichole ; Huang, Yvonne J. Clinical Center: Michigan (University of Michigan) 2022 Am J Respir Crit Care Med 35536732
87 MS067 Characterizing COPD Symptom Variability in the Stable State Utilizing the Evaluating Respiratory Symptoms in COPD Instrument Krishnan, Jamuna K.; Ancy, Kayley M.; Oromendia, Clara ; Hoffman, Katherine L.; Easthausen, Imaani ; Leidy, Nancy K.; Han, Meilan K.; Bowler, Russell P.; Christenson, Stephanie A.; Couper, David J.; Criner, Gerard J.; Curtis, Jeffrey L.; Dransfield, Mark T.; Hansel, Nadia N.; Iyer, Anand S.; Iii, Robert Paine; Peters, Stephen P.; Wedzicha, Jadwiga A.; Woodruff, Prescott G.; Ballman, Karla V.; Martinez, Fernando J. Weill Cornell Medical Center 2022 Chronic Obstr Pulm Dis 35403414
PMC9166327
88 MS217 Risk of COPD exacerbation is increased by poor sleep quality and modified by social adversity Baugh, Aaron ; Buhr, Russell G.; Quibrera, Pedro ; Barjaktarevic, Igor ; Barr, Graham ; Bowler, Russell ; Han, Meilan King; Kaufman, Joel D.; Koch, Abigail L.; Krishnan, Jerry ; Labaki, Wassim ; Martinez, Fernando J.; Mkorombindo, Takudzwa ; Namen, Andrew ; Ortega, Victor ; Paine, Robert ; Peters, Stephen P.; Schotland, Helena ; Sundar, Krishna ; Zeidler, Michelle R.; Hansel, Nadia N.; Woodruff, Prescott G.; Thakur, Neeta Clinical Center: San Francisco (University of California at San Francisco) 2022 Sleep 35665826
89 MS225 Ambient ozone effects on respiratory outcomes among smokers modified by neighborhood poverty: An analysis of SPIROMICS AIR Belz, Daniel C.; Woo, Han ; Putcha, Nirupama ; Paulin, Laura M.; Koehler, Kirsten ; Fawzy, Ashraf ; Alexis, Neil E.; Barr, Graham ; Comellas, Alejandro P.; Cooper, Christopher B.; Couper, David ; Dransfield, Mark ; Gassett, Amanda J.; Han, MeiLan ; Hoffman, Eric A.; Kanner, Richard E.; Krishnan, Jerry A.; Martinez, Fernando J.; Paine, Robert ; Peng, Roger D.; Peters, Stephen ; Pirozzi, Cheryl S.; Woodruff, Prescott G.; Kaufman, Joel D.; Hansel, Nadia N. Clinical Center: Baltimore (Johns Hopkins University) 2022 Sci Total Environ 35318050
PMC9117415
90 MS183 Forced Expiratory Flow at 25%-75% Links COPD Physiology to Emphysema and Disease Severity in the SPIROMICS Cohort. Ronish, Bonnie E.; Couper, David J.; Barjaktarevic, Igor Z.; Cooper, Christopher B.; Kanner, Richard E.; Pirozzi, Cheryl S.; Kim, Victor ; Wells, James M.; Han, Meilan K.; Woodruff, Prescott G.; Ortega, Victor E.; Peters, Stephen P.; Hoffman, Eric A.; Buhr, Russell G.; Dolezal, Brett A.; Tashkin, Donald P.; Liou, Theodore G.; Bateman, Lori A.; Schroeder, Joyce D.; Martinez, Fernando J.; Barr, Graham ; Hansel, Nadia N.; Comellas, Alejandro P.; Rennard, Stephen I.; Arjomandi, Mehrdad ; Iii, Robert Paine Clinical Center: Utah (University of Utah) 2022 Chronic Obstr Pulm Dis 35114743
PMC9166328
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