|Title||SNPMStat v4.0 : Statistical analysis of SNP-disease association with missing genotype data.|
|Year of Publication||2011|
|Authors||Hu, Yi-Juan, Dan-Yu Lin, and Donglin Zeng|
SNPMStat is a command-line program for the statistical analysis of SNP-disease association in case-control/cohort/cross-sectional studies with potentially missing genotype data. SNPMStat allows the user to estimate or test SNP effects and SNP-environment interactions by maximizing the (observed-data) likelihood that properly accounts for phase uncertainty, study design and gene-environment dependence. For SNPs without missing data, the program performs the standard association analysis. For typed SNPs with missing data or untyped SNPs, the program performs the maximum-likelihood analysis described in Lin, Hu and Huang (2008) and Hu, Lin and Zeng (2010).
|Original Publication||SNPMStat v4.0 : Statistical analysis of SNP-disease association with missing genotype data.|