MAP Kinase Signaling System
Anderson, Gray R., Suzanne E. Wardell, Merve Cakir, Lorin Crawford, Jim C. Leeds, Daniel P. Nussbaum, Pallavi S. Shankar, Ryan S. Soderquist, Elizabeth M. Stein, Jennifer P. Tingley et al. "
PIK3CA mutations enable targeting of a breast tumor dependency through mTOR-mediated MCL-1 translation."
Sci Transl Med 8, no. 369 (2016): 369ra175.
Mice
Anderson, Gray R., Suzanne E. Wardell, Merve Cakir, Lorin Crawford, Jim C. Leeds, Daniel P. Nussbaum, Pallavi S. Shankar, Ryan S. Soderquist, Elizabeth M. Stein, Jennifer P. Tingley et al. "
PIK3CA mutations enable targeting of a breast tumor dependency through mTOR-mediated MCL-1 translation."
Sci Transl Med 8, no. 369 (2016): 369ra175.
Mice, Nude
Anderson, Gray R., Suzanne E. Wardell, Merve Cakir, Lorin Crawford, Jim C. Leeds, Daniel P. Nussbaum, Pallavi S. Shankar, Ryan S. Soderquist, Elizabeth M. Stein, Jennifer P. Tingley et al. "
PIK3CA mutations enable targeting of a breast tumor dependency through mTOR-mediated MCL-1 translation."
Sci Transl Med 8, no. 369 (2016): 369ra175.
Molecular Targeted Therapy
Anderson, Gray R., Suzanne E. Wardell, Merve Cakir, Lorin Crawford, Jim C. Leeds, Daniel P. Nussbaum, Pallavi S. Shankar, Ryan S. Soderquist, Elizabeth M. Stein, Jennifer P. Tingley et al. "
PIK3CA mutations enable targeting of a breast tumor dependency through mTOR-mediated MCL-1 translation."
Sci Transl Med 8, no. 369 (2016): 369ra175.
Mutation
Anderson, Gray R., Suzanne E. Wardell, Merve Cakir, Lorin Crawford, Jim C. Leeds, Daniel P. Nussbaum, Pallavi S. Shankar, Ryan S. Soderquist, Elizabeth M. Stein, Jennifer P. Tingley et al. "
PIK3CA mutations enable targeting of a breast tumor dependency through mTOR-mediated MCL-1 translation."
Sci Transl Med 8, no. 369 (2016): 369ra175.
Myeloid Cell Leukemia Sequence 1 Protein
Anderson, Gray R., Suzanne E. Wardell, Merve Cakir, Lorin Crawford, Jim C. Leeds, Daniel P. Nussbaum, Pallavi S. Shankar, Ryan S. Soderquist, Elizabeth M. Stein, Jennifer P. Tingley et al. "
PIK3CA mutations enable targeting of a breast tumor dependency through mTOR-mediated MCL-1 translation."
Sci Transl Med 8, no. 369 (2016): 369ra175.