|Title||Case-cohort studies with interval-censored failure time data.|
|Publication Type||Journal Article|
|Year of Publication||2017|
|Authors||Zhou, Q, H Zhou, and J Cai|
|Date Published||2017 Mar|
The case-cohort design has been widely used as a means of cost reduction in assembling or measuring expensive covariates in large cohort studies. The existing literature on the case-cohort design is mainly focused on right-censored data. In practice, however, the failure time is often subject to interval-censoring; it is known only to fall within some random time interval. In this paper, we consider the case-cohort study design for interval-censored failure time and develop a sieve semiparametric likelihood approach for analyzing data from this design under the proportional hazards model. We construct the likelihood function using inverse probability weighting and build the sieves with Bernstein polynomials. The consistency and asymptotic normality of the resulting regression parameter estimator are established and a weighted bootstrap procedure is considered for variance estimation. Simulations show that the proposed method works well for practical situations, and an application to real data is provided.
|Original Publication||Case-cohort studies with interval-censored failure time data.|
|PubMed Central ID||PMC5608290|
|Grant List||P01 CA142538 / CA / NCI NIH HHS / United States |
R01 ES021900 / ES / NIEHS NIH HHS / United States
Case-cohort studies with interval-censored failure time data.