2014 IMPACT Symposium III - Agenda & Speakers

"Advances in Clinical Trial Statistics: Multiplicity Adjustment and Sequential, Multiple Assignment, Randomized Trials"

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Day 1 (Thursday, November 20th, 2014)
7:30-8:00 AM
Continental Breakfast
Advances in Clinical Trial Statistics: Multiplicity Adjustment
(organized by Fei Zou, UNC, and Dror Rom, Prosoft Clincial)
8:00-8:05 AM
Welcome and Introduction
8:05-9:30 AM
Tutorial: Introduction to Multiplicity in Clinical Trials
Frank Bretz, PhD, Novartis, [Abstract & Slides]
9:30-9:40 AM
9:40-10:20 AM
Keynote Lecture I
Yoav Benjamini, PhD, Tel Aviv University, "In Hochberg’s tradition: Selective Inference for Clinical Trials" [Abstract & Slides]
10:30-11:45 AM
Scientific Session I
Sanat Sarkar, PhD, Temple University, "Improving Holm's procedure using pairwise dependencies" [Abstract]
Joseph Heyse, PhD, Merck, "An Overview of Multiple Testing Procedures for Categorical Data" [Abstract & Slides]
Vered Madar, PhD, University of North Carolina, "Faster algorithm to control the Benjamini-Hochberg false discovery rate and its application for analysis of huge genomic data." [Abstract]
11:45 AM-12:45 PM
12:45-1:35 PM
Scientific Session II
Michael Rosenblum, PhD, Johns Hopkins University, "Optimal, Two Stage, Adaptive Enrichment Designs for Randomized Trials, using Sparse Linear Programming" [Abstract & Slides]
Dror Rom, PhD, Prosoft Clinical, "The Closure Principle Revisited" [Abstract & Slides]
1:35-1:45 PM
1:45-2:25 PM
Keynote Lecture II
Jiangtao Gou & Ajit Tamhane, PhD, Northwestern University, "Hochberg Multiple Test Procedure Under Negative Dependence" [Abstract & Slides]
2:25-2:45 PM
Advances in Clinical Trial Statistics: Sequential, Multiple Assignment Randomized Trials (SMARTs)
(organized by Eric Laber and Marie Davidian, NCSU; Michael Kosorok, UNC-CH)
2:45-2:50 PM
Welcome and Introduction
2:50-4:15 PM
"Tutorial: Getting SMART about Dynamic Treatment Regimes: A Conceptual Introduction"
Danny Almirall, PhD, University of Michigan [Abstract & Slides]
4:15-4:25 PM
4:25-5:05 PM
Keynote Lecture III
Peter Thall, PhD, MD Anderson Cancer Center, "SMART Design, Conduct, and Analysis in Oncology" [Abstract]
5:05-6:15 PM
Poster Session and Reception (combined topics) [Poster Info]
6:15 PM
Dinner (not provided)
Day 2 (Friday, November 21st, 2014)
7:30-8:00 AM
Continental Breakfast
8:00-9:15 AM
Scientific Session III
Yingqi Zhao, PhD, University of Wisconsin-Madison, "Estimation of Optimal Dynamic Treatment Regimes" [Abstract & Slides]
Lu Wang, PhD, University of Michigan, "Evaluation of Viable Dynamic Treatment Regimes in a Sequentially Randomized Trial of Advanced Prostate Cancer" [Abstract & Slides]
Eric Laber, PhD, North Carolina State University, "Sizing a trial for estimation of an optimal treatment regime" [Abstract & Slides]
9:15-9:25 AM
9:25-10:40 AM
Scientific Session III (cont.)
Kelley Kidwell, PhD, University of Michigan, "Addressing the Challenges and Reaping the Benefits of SMARTs" [Abstract & Slides]
Abdus Wahed, PhD, University of Pittsburgh, "Baseline Covariate Adjustment in SMART Studies via Artificial Randomization" [Abstract & Slides]
Yichi Zhang, North Carolina State University, "Interpretable treatment regimes" [Abstract & Slides]
10:40-10:50 AM
10:50-11:30 AM
Keynote Lecture IV
Susan Murphy, PhD, University of Michigan, "Micro-Randomized Trials & mHealth" [Abstract & Slides]
11:30-11:45 AM
Closing remarks and adjournment of scientific session


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