Publications
SMAC: Spatial multi-category angle-based classifier for high-dimensional neuroimaging data." Neuroimage 175 (2018): 230-245.
"DTRlearn: Learning Algorithms for Dynamic Treatment Regimes (R). 1.3 ed., 2018.
Accelerated intensity frailty model for recurrent events data." Biometrics 70, no. 3 (2014): 579-87.
"A unification of models for meta-analysis of diagnostic accuracy studies without a gold standard." Biometrics 71, no. 2 (2015): 538-47.
" Augmented outcome-weighted learning for estimating optimal dynamic treatment regimens." Stat Med 37, no. 26 (2018): 3776-3788.
"Principal Components Adjusted Variable Screening." Comput Stat Data Anal 110 (2017): 134-144.
"Sequential multiple assignment randomization trials with enrichment design." Biometrics 73, no. 2 (2017): 378-390.
"Utility-based Weighted Multicategory Robust Support Vector Machines." Stat Interface 3, no. 4 (2010): 465-476.
"Hard or Soft Classification? Large-margin Unified Machines." J Am Stat Assoc 106, no. 493 (2011): 166-177.
"A Comparison of Monte Carlo Methods for Computing Marginal Likelihoods of Item Response Theory Models." J Korean Stat Soc 48, no. 4 (2019): 503-512.
"Estimating personalized diagnostic rules depending on individualized characteristics." Stat Med 36, no. 7 (2017): 1099-1117.
"Associating somatic mutations to clinical outcomes: a pan-cancer study of survival time." Genome Med 11, no. 1 (2019): 37.
"Estimation of dynamic treatment regimes for complex outcomes: Balancing benefits and risks." In Adaptive Treatment Strategies in Practice: Planning Trials and Analyzing Data for Personalized Medicine, 249-262. Philadelphia: ASA-SIAM, 2016.
"iqLearn: Interactive Q-Learning in R." J Stat Softw 64, no. 1 (2015).
" Interactive Q-learning for Quantiles." J Am Stat Assoc 112, no. 518 (2017): 638-649.
"IQ-Learning., 2012.
DOVE: Durability of Vaccine Efficacy. v1.2 ed., 2021.
SCORE-Seq: Score tests for detecting disease associations with rare variants in sequencing studies (C).. 5.0 ed., 2013.
groupedSurv: Efficient Estimation of Grouped Survival Models Using the Exact Likelihood Function (R). 1.0.0 ed., 2018.
A simple and accurate method to determine genomewide significance for association tests in sequencing studies." Genet Epidemiol 43, no. 4 (2019): 365-372.
" Meta-analysis of genome-wide association studies: no efficiency gain in using individual participant data." Genet Epidemiol 34, no. 1 (2010): 60-6.
"On the relative efficiency of using summary statistics versus individual-level data in meta-analysis." Biometrika 97, no. 2 (2010): 321-332.
"Genetic association analysis under complex survey sampling: the Hispanic Community Health Study/Study of Latinos." Am J Hum Genet 95, no. 6 (2014): 675-88.
"Quantitative trait analysis in sequencing studies under trait-dependent sampling." Proc Natl Acad Sci U S A 110, no. 30 (2013): 12247-52.
"fastJT: Efficient Jonckheere-Terpstra Test Statistics for Robust Machine Learning and Genome-Wide Association Studies (R). 1.0.4 ed., 2017.
Discussion of the Paper by R. L. Prentice and Y. Huang - Optimal Designs and Efficient Inference for Biomarker Studies." Stat Theory Relat Fields 2, no. 1 (2018): 21-22.
"Variable Selection for Nonparametric Quantile Regression via Smoothing Spline AN OVA." Stat 2, no. 1 (2013): 255-268.
"A general framework for integrative analysis of incomplete multiomics data." Genet Epidemiol 44, no. 7 (2020): 646-664.
"Functional-mixed effects models for candidate genetic mapping in imaging genetic studies." Genet Epidemiol 38, no. 8 (2014): 680-91.
" fastJT: An R package for robust and efficient feature selection for machine learning and genome-wide association studies." BMC Bioinformatics 20, no. 1 (2019): 333.
"jtGWAS: Efficient Jonckheere-Terpstra test statistics (R).. 1.0 ed., 2016.
Nonparametric estimation of the mean function for recurrent event data with missing event category." Biometrika 100, no. 3 (2013).
"bcSeq: an R package for fast sequence mapping in high-throughput shRNA and CRISPR screens." Bioinformatics 34, no. 20 (2018): 3581-3583.
"A general framework for detecting disease associations with rare variants in sequencing studies." Am J Hum Genet 89, no. 3 (2011): 354-67.
" intcensROC: Fast Spline Function Based Constrained Maximum Likelihood Estimator for AUC Estimation of Interval Censored Survival Data (R). 0.1.1 ed., 2018.
SEMIPARAMETRIC REGRESSION ANALYSIS OF REPEATED CURRENT STATUS DATA." Stat Sin 27, no. 3 (2017): 1079-1100.
"Sparse concordance-assisted learning for optimal treatment decision." J Mach Learn Res 18 (2018).
"Deep advantage learning for optimal dynamic treatment regime." Stat Theory Relat Fields 2, no. 1 (2018): 80-88.
"Functional Linear Regression Models for Nonignorable Missing Scalar Responses." Stat Sin 28, no. 4 (2018): 1867-1886.
"Bayesian Design of Non-Inferiority Clinical Trials via the Bayes Factor." Stat Biosci 10, no. 2 (2018): 439-459.
"Fitting Cox Models with Doubly Censored Data Using Spline-Based Sieve Marginal Likelihood." Scand Stat Theory Appl 43, no. 2 (2016): 476-486.
"Assessing the dependence of sensitivity and specificity on prevalence in meta-analysis." Biostatistics 12, no. 4 (2011): 710-22.
"Bayesian inference for network meta-regression using multivariate random effects with applications to cholesterol lowering drugs." Biostatistics 20, no. 3 (2019): 499-516.
"TwinMARM: two-stage multiscale adaptive regression methods for twin neuroimaging data." IEEE Trans Med Imaging 31, no. 5 (2012): 1100-12.
"A global logrank test for adaptive treatment strategies based on observational studies." Stat Med 33, no. 5 (2014): 760-71.
"Nucleotide excision repair capacity increases during differentiation of human embryonic carcinoma cells into neurons and muscle cells." J Biol Chem 294, no. 15 (2019): 5914-5922.
"Sample size calculation for cluster randomization trials with a time-to-event endpoint." Stat Med 39, no. 25 (2020): 3608-3623.
"cSFM: Covariate-adjusted skewed functional model (R).. 1.1 ed., 2014.
Weighted Area Under the Receiver Operating Characteristic Curve and Its Application to Gene Selection." J R Stat Soc Ser C Appl Stat 59, no. 4 (2010): 673-692.
"Incorporating covariates in skewed functional data models." Biostatistics 16, no. 3 (2015): 413-26.
"Continual reassessment method with regularization in phase I clinical trials." J Biopharm Stat 30, no. 6 (2020): 964-978.
"Comparison of adaptive treatment strategies based on longitudinal outcomes in sequential multiple assignment randomized trials." Stat Med 36, no. 3 (2017): 403-415.
"A regression approach to ROC surface, with applications to Alzheimer's disease." Sci China Math 55, no. 8 (2012): 1583-1595.
"Multiscale adaptive generalized estimating equations for longitudinal neuroimaging data." Neuroimage 72 (2013): 91-105.
"Weighted area under the receiver operating characteristic curve and its application to gene selection." Journal of the Royal Statistical Society: Series C (Applied Statistics) (2010).
"Efficient estimation of grouped survival models." BMC Bioinformatics 20, no. 1 (2019): 269.
"Secondary analysis of case-control association studies: Insights on weighting-based inference motivate a new specification test." Stat Med 39, no. 22 (2020): 2869-2882.
"Multicategory reclassification statistics for assessing improvements in diagnostic accuracy." Biostatistics 14, no. 2 (2013): 382-94.
"Sample size calculation for studies with grouped survival data." Stat Med 37, no. 27 (2018): 3904-3917.
"Multiscale Adaptive Regression Models for Neuroimaging Data." J R Stat Soc Series B Stat Methodol 73, no. 4 (2011): 559-578.
"Galax (C++)., 2016.
Estimating Bayesian Phylogenetic Information Content." Syst Biol 65, no. 6 (2016): 1009-1023.
" Marginal Structural Cox Models with Case-Cohort Sampling." Stat Sin 26, no. 2 (2016): 509-526.
"BFLCRM: A BAYESIAN FUNCTIONAL LINEAR COX REGRESSION MODEL FOR PREDICTING TIME TO CONVERSION TO ALZHEIMER'S DISEASE." Ann Appl Stat 9, no. 4 (2015): 2153-2178.
"Joint Estimation of Multiple Precision Matrices with Common Structures." J Mach Learn Res 16 (2015): 1035-1062.
"Combining an evolution-guided clustering algorithm and haplotype-based LRT in family association studies." BMC Genet 12 (2011): 48.
"Bayesian analysis of stochastic volatility-in-mean model with leverage and asymmetrically heavy-tailed error using generalized hyperbolic skew Student's t-distribution." Stat Interface 10 (2017): 529-541.
"Discussion of Laber et al. "Optimal treatment allocations in space and time for on-line control of an emerging infectious disease"." J R Stat Soc Ser C Appl Stat 67, no. 4 (2018): 779-780.
"Quantile regression for censored mixed-effects models with applications to HIV studies." Stat Interface 8, no. 2 (2015): 203-215.
"Flexible longitudinal linear mixed models for multiple censored responses data." Stat Med 38, no. 6 (2019): 1074-1102.
"Evaluating personalized treatment regimes." In Methods in Comparative Effectiveness Research. New York: Chapman and Hall/CRC, 2017.
"Functional feature construction for individualized treatment regimes." J Am Stat Assoc 113, no. 523 (2017): 1219-1227.
"Q-Learning. In Wiley StatsRef: Statistics Reference Online. Wiley, 2018.
Discussion of "Combining biomarkers to optimize patient treatment recommendation"." Biometrics 70, no. 3 (2014): 707-10.
"Dynamic treatment regimes: technical challenges and applications." Electron J Stat 8, no. 1 (2014): 1225-1272.
"Dynamic treatment regimes, past, present, and future: A conversation with experts." Stat Methods Med Res 26, no. 4 (2017): 1605-1610.
" Using pilot data to size a two-arm randomized trial to find a nearly optimal personalized treatment strategy." Stat Med 35, no. 8 (2016): 1245-56.
"Statistical Significance and the Dichotomization of Evidence: The Relevance of the for Statisticians." J Am Stat Assoc 112, no. 519 (2017): 902-904.
"Tree-based methods for individualized treatment regimes." Biometrika 102, no. 3 (2015): 501-514.
"Interactive model building for -learning." Biometrika 101, no. 4 (2014): 831-847.
" Set-valued dynamic treatment regimes for competing outcomes." Biometrics 70, no. 1 (2014): 53-61.
"Identifying optimal dosage regimes under safety constraints: An application to long term opioid treatment of chronic pain." Stat Med 37, no. 9 (2018): 1407-1418.
"Optimal treatment allocations in space and time for on-line control of an emerging infectious disease." J R Stat Soc Ser C Appl Stat 67, no. 4 (2018): 743-770.
"Phase II clinical trials with time-to-event endpoints: optimal two-stage designs with one-sample log-rank test." Stat Med 33, no. 12 (2014): 2004-16.
"Optimal estimation for regression models on τ-year survival probability." J Biopharm Stat 25, no. 3 (2015): 539-47.
"Comparison of operational characteristics for binary tests with clustered data." Stat Med 34, no. 15 (2015): 2325-33.
"Optimal two-stage log-rank test for randomized phase II clinical trials." J Biopharm Stat 27, no. 4 (2017): 639-658.
"Pharmacogenetics, enzyme probes and therapeutic drug monitoring as potential tools for individualizing taxane therapy." Pharmacogenomics 14, no. 5 (2013): 555-74.
"Precision Medicine." Annu Rev Stat Appl 6 (2019): 263-286.
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